The COVID-19 pandemic has caused widespread illness, death, and economic disruption around the world. At the same time, malaria continues to be a leading cause of death in many countries. This study aims to examine the relationship between COVID-19, malaria, and occupation. It was a cross sectional study of 400 COVID-19 positive patients. Data were collected through questionnaires and blood samples collected and examined for malaria parasite. The data gotten was analyzed using graph pad prism Version 8.0.2.263. Results gotten reveals that risk factors are not significantly associated with occupation, Prevalence of malaria is not significantly associated with occupation, the level of Parasitaemia is not significantly associated with occupation and Symptoms are also not significantly associated with occupation at p>0.05. The study has confirmed that risk factors, prevalence of malaria, severity of parasitaemia and symptoms have no association with occupation. These findings highlight the need for targeted interventions to protect other populations, including measures to improve access to personal protective equipment and treatment for COVID-19 and malaria.