This research is categorized as Research and Development (R&D) as developed in this research is a learning media Math BRAINO, a Mathematics Braille Dominos for visually disabled students. This research adopted ADDIE as an R&D model that stands for Analysis, Design, Development, Implementation, and Evaluation. The purpose of this study was to describe the development process and to produce mathematics learning media for visually disabled students, as well as to determine the effectiveness of the Math BRAINO-Mathematics Braille Dominos. To determine its practicability and effectiveness, it requires validation from the experts and a trial. Based on the data analysis result, it can be concluded that the product, Math BRAINO, are valid, reaching 94,1% with the category of excellent for the learning media. The reviewer of media mentioned that by the aspect of physical and look, including size, material, durability, quality, and color, the product reaches 96% with the category of very good. From the viewpoint of its practicality and simplicity to use, the product developed is categorized as great in the score of 96%. While based on the Braille handwriting aspect, it reaches 80%, belonging to the category of good. Meanwhile, according to the mathematics content, the product falls into the score of 78,3 % with the category of good.