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The use of new feed factors in poultry feeding is necessarily reflected in the change in blood parameters. The article presents the results of physiological studies on the study of changes in the hematological parameters of laying hens with the additional use of enzyme preparations Sanzaym and Sanfayz 5000, as well as lecithin in their feeding. Scientific and economic experience, during which the main physiological indicators were studied, was carried out in the State Unitary Enterprise of the Breeding Reproductor "Urus-Martanovsky" of the Chechen Republic on laying hens of the Loman Brown breed. As the main diet in the experiment, compound feed was used, prepared on the basis of corn, barley, wheat, sunflower meal. It was fed to a bird of the control group. In addition to the main diet, the livestock of the 1 experimental group were additionally fed two enzyme preparations: Sanzaym (100 g/t of feed) and Sanfayz 5000 (80 g/t of feed). Phospholipid lecithin, in the amount of 10 g/kg of feed, was fed to livestock. The use of enzyme preparations and lecithin increased egg production per average carrier by 24.5 pcs or 8.9%, the intensity of egg production by 7.42%, which made it possible to obtain 245.4 kg or 14.6% more egg mass than the control group.