Objective: To assess the frequency of bacterial agents in chronic suppurative otitis media and the antibiotic susceptibility patterns of isolates among patients.Methods: A total of 185 patients clinically diagnosed with chronic suppurative otitis media were interviewed and middle-ear effusion samples were collected using sterile swabs. All bacterial isolates were identified by conventional microbiological methods. Antibiotic susceptibility patterns of the isolates were determined by Kirby-Bauer disc diffusion.Results: Staphylococci spp. (64.9 per cent) were the most prevalent bacteria isolated, followed by Klebsiella spp. (12.9 per cent) and Pseudomonas aeruginosa (10.3 per cent). The most effective antibiotic for treatment of bacterial chronic suppurative otitis media was ciprofloxacin. Statistical analysis showed no significant difference in bacterial infestations among chronic suppurative otitis media patients and the antimicrobial susceptibility patterns of the bacterial isolates based on gender and age ( p > 0.05).Conclusion: Our findings highlight the importance of a continuous and periodic evaluation of the bacteriological profile and antibiotic susceptibility patterns in chronic suppurative otitis media patients for efficacious treatment of the infection.
The incidence of shigellae was measured in 445 children with diarrhoea in Sanandaj, Kordestan, and 715 in Tehran during a 1-year study. 18 (4%) patients in Sanandaj and 41 (5.7%) patients in Tehran were positive for various shigella species. Sh. boydii (7 strains) and Sh. sonnei (25 strains) were the commonest species in Sanandaj and Tehran respectively. Among the isolates from Sanandaj the highest resistance was to tetracycline (55.5%), whereas in Tehran it was to sulfamethoxazole/trimethoprim (68.3%).
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