Abstract:Objective(s): The aim of this study was to evaluate the association of serum C-reactive protein (CRP)

Background: Coronavirus disease-2019 (COVID-19) has spread across the globe and has been declared pandemic by the World Health Organization (WHO). People of all age groups are at risk of getting the disease. Pregnant women are at an increased risk of acquiring the infection and developing moderate-to-severe pneumonia resulting in adverse outcome. Case Descriptions: Published case series have shown that high-risk pregnancies have been associated with higher morbidity and mortality. Pregnancy-induced immune response might have an impact on maternal cardiovascular system and exaggerate the course of COVID-19 disease. Here, we report two cases of late pregnancy with COVID-19 one of which ended with complete recovery and another with adverse outcome. Conclusion: These two case scenarios might add to the emerging evidence of pregnancy outcome in COVID-19.

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Introduction During the COVID-19 pandemic, healthcare workers had a high workload and were exposed to multiple psychosocial stressors. However, a knowledge gap exists about the levels of burnout among Bangladeshi frontline doctors during this COVID-19 pandemic. The study investigated burnout syndrome (BOS) among frontline doctors in two public secondary and tertiary care hospitals in Chattogram, Bangladesh. Materials & methods This cross-sectional study involved frontline doctors working at two hospitals treating COVID-19 and non-COVID patients from June to August 2020. A self-administered questionnaire that included Maslach Burnout Inventory for Human Services Survey (MBI-HSS) was used to capture demographic and workplace environment information. ANOVA and t-test were used to determine the statistical differences in the mean values of the three dimensions of MBI-HSS. Scores for three domains of burnout: emotional exhaustion (EE), depersonalization (DP), and personal accomplishment (PA) were calculated. Post-hoc analysis was done to identify the significant pair-wise differences when the ANOVA test result was significant. Multiple logistic regression was performed to determine the influence of factors associated with BOS. Results A total of 185 frontline doctors were invited to participate by convenience sampling, and 168 responded. The response rate was 90.81%. The overall prevalence of BOS was 55.4% (93/168) (95% CI: 47.5% to 63.0%). Moderate to high levels of EE was found in 95.8% of the participants. High DP and reduced PA were observed in 98.2% and 97% of participants. Younger age (25–29 years), being female, and working as a medical officer were independently associated with high levels of burnout in all three domains. EE was significantly higher in females (P = 0.011). DP was significantly higher in medical officers, those at earlier job periods, and those working more than 8 hours per day. Conclusion During the COVID-19 outbreak, BOS was common among Bangladeshi frontline doctors. Females, medical officers, and younger doctors tended to be more susceptible to BOS. Less BOS was experienced when working in the non-COVID ward than in the mixed ward.

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