Apophysomyces elegans is an uncommon human pathogen that causes deeply invasive infections in immunocompromised patients and cutaneous infection in immunocompetent patients. We report the development of severe deep soft tissue zygomycosis caused by A. elegans in an otherwise healthy child after trauma. She was successfully treated with surgical debridements and antifungal therapy with liposomal amphotericin B. A review of the literature indicates that zygomycosis caused by A. elegans is associated with traumatic inoculation.
Pediatric tuberculosis (TB) in Canada is mainly diagnosed in Aboriginal and foreign-born children, and children of foreign-born parents. • About one-third of adolescents with TB in Canada have extrathoracic disease. • Tuberculosis may mimic many conditions: specimens for TB culture are crucial for diagnosis. • Best results are achieved if treatment is conducted by a team that includes physicians with experience in the management of pediatric TB.
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