Foodborne diseases caused by pathogenic bacteria pose a serious threat to human health.  Early and rapid detection of foodborne pathogens is  urgently needed. The use of biosensors to  identify and detect pathogenic bacteria has attracted ample attention because of its high sensitivity, near real-time quantification without enrichment, on-site detection, simple operation and more. As a promising alternative recognition element in biosensors, lectin has been widely studied in bacterial detection because of its high stability and low cost. In...

Foodborne diseases caused by pathogenic bacteria pose a serious threat to human health. Early and rapid detection of foodborne pathogens is an urgent task for preventing disease outbreaks. Microfluidic devices are simple, automatic, and portable miniaturized systems. Compared with traditional techniques, microfluidic devices have attracted much attention because of their high efficiency and convenience in the concentration and detection of foodborne pathogens. This article firstly reviews the bio-recognition elements integrated on microfluidic chips in recent years and the progress of microfluidic chip development for pathogen pretreatment. Furthermore, the research progress of microfluidic technology based on optical and electrochemical sensors for the detection of foodborne pathogenic bacteria is summarized and discussed. Finally, the future prospects for the application and challenges of microfluidic chips based on biosensors are presented. Graphical abstract

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Au-4MBA@Ag with a strong Raman signal was successfully synthesized, and combination with magnetic separation technology achieved sensitive detection of cTnI.