Poultry has become a great important for producing meat and egg to face increasing in the world population size form year to the next. In recent years, poultry were used as an experimental animal model in medical research and pharmaceutical industry because of its advantages. The current review will indicate the different application of poultry and its products in wide application in biotechnology in medical research and pharmaceutical industry to study and treatment human diseases. Also, some of poultry diseases viruses used for treatment of human diseases. Using of poultry and chick embryos in medical research and pharmaceutical industry will witness great developments according to the latest knowledge in cell and animal transgenesis in the near future.