TC sign is more accurate than hepatobiliary scan and has acceptable sensitivity and specificity for diagnosis of BA.

Identification of risk factors and their importance in different genders is essential in order to prevent, diagnose, and manage coronary artery disease (CAD) properly. The present study aims to investigate the role of gender in the distribution of different risk factors in ischemic heart disease. This study is a cross-sectional study. More than one thousand (N = 1012) patients referring to the Nuclear Medicine Department in Namazi Hospital, Shiraz, Iran, from March 2017 to March 2018 were studied. The patients’ demographic data and their clinical history were collected. The results of the myocardial perfusion scan were recorded and compared between groups. Statistical analysis was implemented by SPSS version 18.0, and P values below 0.05 were considered statistically significant. Out of the 1012 patients participating in this study, 698 (69%) were female and 314 (31%) were male. Ischemic heart disease (IHD) was significantly higher in men compared to women (19.1% versus 14.2%). The higher levels of systolic and diastolic blood pressures, along with older age, were a significant risk factor in women P<0.05. Previous myocardial infarction (MI), diabetes mellitus (DM), hypertension (HTN), and hyperlipidemia (HLP) had a strong correlation with IHD in our female population. Regarding the male subjects, previous MI and HLP had a lower correlation with IHD. Based on our logistic regression models, investigation of the simultaneous effects of risk factors on IHD showed that previous MI is the most effective risk factor in females (OR = 3.93) mostly in terms of residual ischemia in the infarcted myocardium. In the male population, on the other hand, HTN was identified as the most effective risk factor for IHD (OR = 2). In conclusion, we found that older age, higher blood pressure, DM, previous MI, HTN, and HLP have a significant association with IHD in the female population, whereas older age, DM, and HTN were significant risk factors for IHD in males. Also, the most effective factor for women was previous MI, while it was HTN for the male population.

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Whole body bone scan with Technetium-99m MDP (methylene diphosphate) can detect bony lesions due to altered osteoblastic activity.Non-physiologic or increased radiotracer uptake in the bony structures of patients with a history of malignant diseases is usually interpreted as being suspicious of bone metastasis. It is extremely important to properly distinguish false positive sites of Tc-99m MDP localization. We present three patients with the same pattern of Tc-99m MDP abnormality in different locations. These scans were all performed on the same day to evaluate possible bone metastases in three patients with breast carcinoma. After careful examination, repeated images revealed bed clothing contamination. This is different from bed contamination by displacement among different patients. It is also different from detector contamination by limited area of involvement where detector contamination appears as a line throughout the total body projection. It can be helpful if a nuclear medicine specialist has a brief look at all scans prior to reporting them. In cases where the same pattern of abnormality is repeated in all images, the possibility of technical error such as bed clothing contamination rather than a pathological abnormality should be borne in mind.