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BackgroundPrevalence of diabetes mellitus type 2 (DM) is increasing globally. Considering the potential role of poly-unsaturated fatty acids in prevention of DM type 2 and lipid profiles improvement, some studies have been carried out on walnut. However, there are no studies on control of blood sugar in DM type 2 patients using walnut.ObjectivesThe current study aimed to evaluate the effect of walnut oil on blood sugar in DM type 2 patients.MethodsThis randomized control clinical trial was performed on 100 patients with DM type 2. For the experiment group (n = 50), walnut oil (15 g/day for three months) was added to their diet, while the control group (n = 50) did not undergo any interventions. Before initiation of the experiment and after the experiment, the systolic and diastolic blood pressure (SBP and DBP) levels, fasting blood sugar (FBS) and HbA1c were measured.ResultsThe two groups were not significantly different for SBP, DBP, body weight, and Body Mass Index. HbA1c level decreased significantly in the experiment group by 7.86% ± 21.97 (P = 0.005) from 7.00 ± 1.08 before the intervention to 6.37 ± 1.29 after the intervention. Also, FBS level decreased significantly by 8.24% ± 16.77 (P = 0.001); from 158.37 ± 48.16 before the intervention to 137.91 ± 23.24 after the intervention in the experimental group. These changes in the control group were not significant.ConclusionsConsumption of walnut oil (15 g/day for three months) was shown to improve blood glucose level but, no changes were noted for bodyweight and blood pressure in type two diabetic patients.

Background: Metabolic syndrome, which includes multiple metabolic disorders in an individual, has a direct relationship with incidence of various heart diseases. Satureja hortensis L. has been considered to treat this syndrome because its active compounds have valuable therapeutic effects, including anti-inflammatory, antihyperglycemic, vasodilator, and antihyperlipidemic properties as well as being antioxidants and free radical scavengers.

Metabolic syndrome, also known as insulin resistance disorder, is the simultaneous manifestation of multiple metabolic disorders in an individual. The present-day complementary and alternative therapies suggest several medicinal herbs that may have the potential to improve one or multiple complications of metabolic syndrome. All of them have their own limitations in efficacy and unwanted effects. Therefore, we reviewed species of Satureja as widespread medicinal herbs and potentially good remedies for metabolic syndrome. We reviewed literature found in PubMed and the ISI Web of Knowledge with the key word Satureja in the title. The influence of any species of Satureja on any disease or syndrome, enzymatic, metabolic, or physiological pathways, in human, animals, or in vitro conditions related to any characteristics of metabolic syndrome were considered. The main outcomes of treatment with Satureja species were categorized, and the possible mechanisms of action are discussed in this article.

The current trial investigates the effect of renal diet therapy and nutritional education on the estimated Glomerular Filtration Rate (eGFR), blood pressure, and depression among patients with CKD. A total of 120 CKD patients (stages 3-4) (15<eGFR<60) were randomized into an intensive nutrition intervention group (individualized renal diet therapy plus nutrition counseling: 0.75 g protein/kg/day and 30-35 kcal/kg/day with sodium restriction) and a control group (routine and standard care) for 24 weeks. The primary outcome was the change in the eGFR. Secondary outcomes included changes in anthropometric measures, biochemistry [serum creatinine (Cr), uric acid, albumin, electrolytes, calcium, vitamin D, ferritin, Blood Urea Nitrogen (BUN), and hemoglobin], blood pressure, nutritional status, depression, and quality of life. The eGFR increased significantly in the intervention group compared with the control group (p<0.001). Moreover, serum levels of Cr and the systolic and diastolic blood pressures decreased significantly in the intervention group relative to the control group (p<0.001, p<0.001, and p=0.020, respectively). The nutrition intervention also hindered the increase in the BUN level and the depression score (p=0.045 and p=0.028, respectively). Furthermore, the reduction in protein and sodium intake was greater in the intervention group (p=0.003 and p<0.001, respectively). Nutritional treatment along with supportive education and counseling, contributed to improvements in renal function, blood pressure control, and adherence to protein intake recommendations. A significant difference in the mean eGFR between the groups was also confirmed at the end of the study using analysis of covariance (ANCOVA) (Β=-5.06; 95% CI: -8.203, -2.999).