MiR146a (rs2910146) and MiR499 (rs3746444) gene polymorphisms may be genetic determinants for increased risk of chronic periodontitis and peri-implantitis in Iranians. More studies with larger sample sizes in different populations are necessary for determining the effect of these SNPs.
Aim:Endodontic treatment generally reduces the fracture resistance of teeth. The purpose of this study was to evaluate the fracture resistance and the mode of fracture of endodontically treated human premolars with different amounts of remaining tooth structure.Materials and Methods:Seventy non-carious human premolars were randomly assigned into 7 groups. Group 1 (ST) did not receive any preparation. The teeth in groups 2-7 received root canal treatment and different preparations. Group 2 (MO-NF): Mesio-occlusal preparation without filling; Group 3 (MOD-NF): Mesio-occluso-distal preparation without filling; Group 4 (MO-F): Mesio-occlusal preparation with direct composite restoration (Z250); Group 5 (MOD-F): Mesio-occluso-distal preparation with direct composite restoration (Z250); Group 6 (CC-D): Mesio-occluso-distal preparation with cusp reduction and direct composite restoration (Z250); Group 7 (CC-InD): Mesio-occluso-distal preparation with cusp reduction and indirect composite restoration (Gradia GC). The fracture resistance (N) was assessed under compressive load in a universal testing machine (Zwick) perpendicular to the occlusal surface at a cross-head speed of 1 mm/min, and the mode of fracture was assessed under stereomicroscope.Statistical analysis:Data was analyzed by Kruskal – Wallis and Mann – Whitney tests and the mode of fracture was analyzed by Chi-square test (P < 0.05).Results:Statistical analysis showed that MO and MOD cavity preparations significantly reduced the fracture resistance of sound teeth. Direct composite restorations can improve the fracture resistance, and Groups 7 and 6 presented the highest fracture resistance values.Conclusions:Teeth with adhesive restorations showed significantly higher fracture resistance values as compared with the non-restored ones.
Background and aims. The goal of this study was to evaluate the clinical efficacy of a standard oral hygiene routine (daily tooth brushing and flossing) along with cetylpyridinium chloride (CPC) mouthwash in comparison to the same protocol without mouthwash in chronic periodontitis patients during a 14-day period. Materials and methods. This comparative study was carried out or 50 non-smoking patients with chronic periodontitis; 25 patients followed an oral hygiene regimen using a toothbrush and dental floss (control group) and the remaining 25 used the mentioned protocol along with CPC mouthwash (test group) for 14 days. The plaque index (PI), modified gingival index (MGI) and probing pocket depth (PPD) were assessed. Wilcoxon and Mann-Whitney U tests were used to evaluate and compare the prevalence of indices between the two groups. Statistical significance was set at P<0.05. Results. The results showed greater improvement of MGI in the test group (P=0.001). No statistically significant differences were observed in PI (P=0.47) and PPD (P=0.43) between the two groups. Conclusion. Adding mouthwash to a standard oral hygiene regimen may improve some clinical gingival parameters when compared with an oral hygiene routine without a mouthwash
Cigarette smoking and tobacco consumption are serious hazards threatening the health of human beings. Several strategies have been proposed for smoking cessation in patients presenting to medical centers to seek treatment. Some believe that the dental profession plays a key role in quit smoking programs due to its extensive and long-term relationship with patients. Use of known strategies to create motivation for quitting smoking among patients has yielded relatively optimal results. However, it seems that patients' attitudes toward smoking can be changed if we enhance their knowledge about the hazards of tobacco consumption and its adverse effects on dental and oral health and especially the health of dental implants' surrounding structures. This study reports smoking cessation in two patients requiring dental implant treatment. Twenty-eight months after loading of implants, treatment success was confirmed by use of clinical and radiographic indices. No sign of peri-implant disease was detected and the patients were eagerly following the smoking cessation program. It seems that contemporary dental treatments, especially dental implant therapy, can provide a good opportunity to create the motivation required for lifestyle changes in patients.
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