Background Wolff-Parkinson-White (WPW) syndrome is a condition characterized by the persistence of an accessory pathway responsible for ventricular pre-excitation that can lead to symptomatic and potentially severe arrhythmias. Coexistence with atrial fibrillation is well known and not uncommon, exposing to potential degenerescence into ventricular fibrillation when atrial impulses are transmitted along the accessory pathway. WPW syndrome is most prevalent in younger patients and cases revealed after an advanced age have rarely been described in the literature. Case presentation Here, we report a case of atrial pre-excitation first diagnosed at the age of 72 years that required external electrical cardioversion with a favorable outcome. The diagnosis was based on clinical and electrographic findings. Conclusions WPW syndrome is a relatively rare cardiac disorder that can be a cause of sudden death, especially when combined with atrial fibrillation. Therefore, cardiologists have to consider this diagnosis in patients presenting clinical signs of arrhythmia with an electrical pattern of WPW.

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Background: Wolff-Parkinson-White (WPW) syndrome is a condition characterized by the persistence of an accessory bundle responsible for ventricular pre-excitation that can lead to symptomatic and potentially severe arrhythmias. Coexistence with atrial fibrillation is well known and not uncommon, exposing to potential degenerescence into ventricular fibrillation when atrial impulses are transmitted along the accessory pathway. WPW syndrome is most prevalent in younger patients and cases revealed after an advanced age have rarely been described in the literature. Case presentation: Here, we report a case of atrial pre-excitation first diagnosed at the age of 72 years that required external electrical cardioversion with a favorable outcome. The diagnosis was based on clinical and electrographic findings. Conclusions: WPW syndrome is a relatively rare cardiac disorder that can be a cause of sudden death, especially when combined with atrial fibrillation. Therefore, cardiologists have to consider this diagnosis in patients presenting clinical signs of arrhythmia with an electrical pattern of WPW.

Background: Acromegalic cardiomyopathy is a significant cardiovascular complication associated with acromegaly, a rare condition caused by excessive growth hormone production from a pituitary adenoma. While acromegaly often presents with distinct physical changes, early diagnosis can be challenging due to its insidious nature, leading to delayed recognition and the presence of multiple comorbidities at the time of diagnosis. Cardiovascular disease is the most common comorbidity in acromegaly, contributing to significant morbidity and mortality. Case presentation: This case report describes a non-hypertensive patient who presented with biventricular hypertrophy, revealing the presence of acromegalic cardiomyopathy at the age of 54. The diagnosis relied on information from clinical examination, imaging tests, and biological data. The patient successfully underwent transsphenoidal surgery to remove the pituitary adenoma, resulting in a positive outcome. Conclusions: Acromegaly patients have higher mortality rates compared to healthy individuals due to the wide array of associated comorbidities, consequently leading to a reduced life expectancy. Hence, early diagnosis and management, particularly before the age of 40, play a crucial role in mitigating the cardiovascular risks associated with acromegaly.

Twiddler syndrome is an exceptional cause of dysfunction of cardiac prostheses resulting from a displacement of the probe either by deliberate or unconscious manipulation. We report the case of a man admitted for a respiratory arrest (ACR) caused by an extreme bradycardia. Initially implanted 6 weeks earlier for idiopathic ventricular fibrillation without documented ischemic causes or major conduction disorders. The patient has benefited from extraction with reimplantation of a new defibrillation probe. The originality of this observation is underlined by the occurrence of a previously unrecognized inaugural syncopal atrioventricular block revealing Twiddler syndrome in a patient initially implanted with a secondary prevention defibrillator for idiopathic ventricular fibrillation.