This study analyzed the effect of communication on a career mediated by the leader member exchange with Political Skill as a moderating variable. The sampling method used in this study is a saturated sample that was distributed to all employees and lecturers at one of the University in Jakarta, with a population of 149 people. By distributing questionnaires to as many as the population within 2 weeks and the questionnaires that were successfully answered were 97 questionnaires via google form. Data analysis method in this study uses Partial Least Square with the help of Smart PLS software. The results of this study indicate: H1 Communication on career with a significant level of 0.002, H2 The quality of leader member exchange (LMX) affects career by 0,000, while H3 Communication has no effect on careers mediated by the quality of leader member exchange by 0.582, H4 The quality of leader member exchange has no effect on careers by 0.730 and H5 Quality superior-subordinate relations do not affect the career moderated by political expertise by 0.396.