The gastroprotective effect of two plants of La Pampa province Equisetum giganteun L. and Cortaderiaselloana (Schult&Schult. f.) were utilised in an ulcer incited model by hypothermia and immobilisation in rats. Aerial parts of the plants were dried in a heater by air flow at 60 °C. The vegetable drug was extracted by ethanol:water solvent (1:1, v/v). The Mus musculus rats were allotted in groups of five animals each. The observer group (OG) received an oral dose of 0,5 ml of excipient (Ex) composed by carboxymethylcellulose and tween 80 (1:1, v/v). The control group (CG) received 0,05 mg/kg of atropine subcutaneously and 0,5 ml of Ex orally, by contrast, the treated groups (GTEg and GTCs) received an oral dose of 1 gram hydro-alcoholic extract. The results, of both control and treatments groups, were compared and analysed with the results of the observed group by the student t-test. The atropine administered to the CG prevented the ulcer formation in all animals group. The two evaluated plants showed significant gastroprotective effect (p≤0,01) in relation to the CG. It concluded that the extract of the evaluated plants prevented the ulcer formation induced by stress in rats.
Actividad gastroprotectora de Equisetum giganteum L. n.v. cola de caballo y Cortaderia selloana (Schult & Schult. f.) n.v. cortadera en ratones sometidos a estrés e indometacina.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.