No abstract

LESS sacrocolpopexy performed with conventional instruments is feasible and a safe procedure reproducing surgical steps of conventional laparoscopic or robotic surgery.

Pancreatic elastase-1 is a proteolytic enzyme exclusively produced in the pancreas, is stable when passing through the bowel, and its determination is associated with chronic pancreatitis. The clinical diagnosis of pancreatitis is based on anamnesis, physical examination, radiological, sonographic, endoscopic, and laboratory findings. Nowadays, there is a test for the determination of fecal elastase-1, by enzymatic reaction (enzyme-linked immunosorbent assay, ELISA), which specifically determines human elastase-1, promoting the pancreatic function evaluation. Parameters such as linearity, calibration curve, sensitivity, specificity, precision, accuracy, recovery, and receiver operator characteristic (ROC) curve are used to evaluate the test. The aim of this study was the validation of the immunoenzymatic assay (ELISA) and the use of its results in patients with HIV, alcoholics, and under antiretroviral therapy. The study involved 157 patients, 95 of them were HIV-infected, and 62 were completely healthy. The elastase-1 ELISA kit from Bioserv was used, and we noted that the obtained results were linear, sensitive, precise, and accurate. Moreover, our results suggest that this test can be a laboratory evaluation to determine the relationship of pancreatitis with alcohol use, but not its association with antiretroviral use in HIV patients (P=0.424). This test is useful to diagnose pathologies related to pancreatic insufficiency.

Pancreatic involvement in AIDS is very important and common, but there are few studies in the literature concerning the pancreas in AIDS. Therefore, our research involves an important issue in the pancreatic field. The objective of the study was to evaluate the profile of HIV-infected patients with probable exocrine pancreatic insufficiency and its relation to the degree of human immunodeficiency virus (HIV) infection. This is a cross-sectional study carried out at Faculdade de Medicina do ABC in partnership with the basic health care unit Vila Guiomar in Santo André. We selected 118 individuals divided into four groups (a control group and three other groups composed of AIDS patients, separated according to CD4 levels); participants had an interview, completed a questionnaire, and had laboratory and imaging tests. The only clinical variables with significant differences among the studied groups were the use of highly active antiretroviral therapy (HAART), the incidence of opportunistic infections, the administration of chemoprophylaxis, and weight loss. There were no differences in the amylase, lipase, and steatocrit dosages among the groups. Levels of fecal elastase 1 were lower in the HIV patient groups (2, 3, and 4) when compared with the control group, although all of them showed average levels that were much higher than the cutoff point (200 μg/g). Only nonalcoholic individuals showed a relationship between diarrhea and alterations in elastase levels. A relationship between the use of HAART and exocrine pancreatic insufficiency in different phases of HIV infection could not be verified.

Introdução: A elevada demanda por atendimento urológico em São Bernardo do Campo gera uma espera para que pacientes sejam atendidos pelo urologista, após terem sido encaminhados pelo clínico. Objetivos: Avaliar condições associadas a encaminhamentos aos ambulatórios de Urologia da Faculdade de Medicina do ABC, no município. Métodos: Foram avaliados 106 relatórios de encaminhamento de pacientes para consulta urológica em São Bernardo do Campo, entre dezembro de 2009 e março de 2010, e sua correlação com os dados obtidos em consulta urológica. Resultados: Os principais motivos para encaminhamento urológico foram o exame da próstata (29,2%) e a urolitíase (22,6%). Houve concordância entre o motivo referido e o diagnóstico após consulta urológica em 55,7% dos casos, discordância em 20,8% e ausência de menção do motivo da consulta em 23,6%. Observouse que 56,6% dos pacientes não levaram os exames mínimos necessários à consulta com o especialista. Dos encaminhamentos por disfunções sexuais, 17% referiam o real motivo para consulta. Houve concordância em 100% dos encaminhamentos de pacientes oncológicos. Médicos formados há mais de 30 anos encaminharam pacientes mais precisamente. Conclusão: A imprecisão no encaminhamento aos ambulatórios de Urologia e a inexistência de protocolos para tal contribuem para a morosidade do sistema. Propõe-se o uso de protocolos para solicitar exames, previamente ao encaminhamento ao urologista, e o reforço quanto à importância da precisão do encaminhamento junto aos médicos responsáveis pela atenção primária.