Considering that ameloblastomas, in contrast to the other studied tumours, were consistently reactive for calretinin, this protein may have a role in the pathogenesis of this aggressive neoplasm.

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The clinicopathologic characteristics of the current Iranian population are similar to most other reports with a predilection for the posterior mandible, 3rd decade and female subjects; however, there were variations in microscopic features of the studied cases. Clinical significance: Clinical and histologic information on OM in different populations may be useful in clinical settings and treatment planning. Reporting more detailed histologic data can help clarify the biology of this tumor and aid in its histopathologic diagnosis. i

ARTICLE INFOBackground: Odontogenic tumors are derived from the epithelial and/or mesenchymal remnants of the tooth-forming apparatus. Therefore, they are found exclusively in tooth-bearing areas. Similar to other neoplasms in the body, odontogenic tumors tend to histologically mimic the cell or tissue of origin. Case Report: A 5-year-old boy presented with a chief complaint of pain in the mandible which started 3 months ago. Oral examination revealed bony expansion and a radiopaque mass fused with the roots of deciduous second molar was detected during radiographic examination. After surgical excision of the lesion and the involved tooth, microscopic examination revealed neoplastic tissue consisted of trabeculae of mineralized material with irregular lacunae and prominent basophilic reversal lines. Each trabecula was lined by prominent cells surrounded by cellular connective tissue. The lesion infiltrated the pulp chamber and root canals. Conclusion: According to the clinical and radiographic findings, bone-producing tumors, odontogenic tumors with calcifications and reactive lesions were included in the differential diagnosis. However, based on histopathology and radiographic data, final diagnosis of Cementoblastoma, a benign odontogenic tumor, was confirmed. Patient follow-up revealed no recurrence of the lesion.