No abstract

Desmoplastic fibroma is a rare, benign fibrous tumor of bone which is locally aggressive. The mandible is the most prevalent affected of the facial bones. Nevertheless, reports of desmoplastic fibroma affecting the mandible are seldom in the literature. It causes bone destruction and has a high tendency for local recurrence. In this case report, we report a case of desmoplastic fibroma which is located in mandibular angle and extended to coronoid process, in 20-year-old female patient. © 2019 Tehran University of Medical Sciences. All rights reserved. Acta Med Iran 2019;57(7):456-460.

Background and Aim: Oral mucosal lesions have various prevalence rates among different populations. Few studies have evaluated the frequency of oral mucosal lesions in Iranian population. This study aimed to determine the frequency of oral mucosal lesions and the related factors. Methods and Materials:This descriptive study was conducted based on the data in the archives of two referral centers, including the Pathology Departments of the Cancer Institute of Imam Khomeini and Buali hospitals in Tehran, from June 2000 to July 2014. Age, sex, location of the lesions and microscopic diagnosis were retrieved from the files, and the data were analyzed by SPSS13 using Chi-square test. Results: Among 59273 files, 976 patients (1.56%) had oral mucosal lesions, and the most prevalent pathologies were epithelial lesions (89.4%), followed by connective tissue lesions (6.5%). Squamous Cell Carcinoma (53%) was the most prevalent epithelial lesion. The most common location of oral mucosal lesions was the lips (27.8%). Mean age of the patients was 44 ± 3 years. The incidence of mucosal lesions increased with age, while no correlation was observed between mucosal lesions and sex (P<0.9). Conclusion: The most prevalent oral mucosal lesion was the Squamous Cell Carcinoma, which is a malignant tumor with epithelial origin, and its early diagnosis is necessary.

This new marker could help clinicians to determine the prognosis of oral cancer, so it has an effect on optimal treatment.

ARTICLE INFOBackground: Odontogenic tumors are derived from the epithelial and/or mesenchymal remnants of the tooth-forming apparatus. Therefore, they are found exclusively in tooth-bearing areas. Similar to other neoplasms in the body, odontogenic tumors tend to histologically mimic the cell or tissue of origin. Case Report: A 5-year-old boy presented with a chief complaint of pain in the mandible which started 3 months ago. Oral examination revealed bony expansion and a radiopaque mass fused with the roots of deciduous second molar was detected during radiographic examination. After surgical excision of the lesion and the involved tooth, microscopic examination revealed neoplastic tissue consisted of trabeculae of mineralized material with irregular lacunae and prominent basophilic reversal lines. Each trabecula was lined by prominent cells surrounded by cellular connective tissue. The lesion infiltrated the pulp chamber and root canals. Conclusion: According to the clinical and radiographic findings, bone-producing tumors, odontogenic tumors with calcifications and reactive lesions were included in the differential diagnosis. However, based on histopathology and radiographic data, final diagnosis of Cementoblastoma, a benign odontogenic tumor, was confirmed. Patient follow-up revealed no recurrence of the lesion.