Background: The child labor situation has been associated with precarious job conditions and poor health conditions because children are often exposed to unsafe work environments, stressful psycho-social work conditions, scarce or no access to protective services, and heavy work burdens. Objective: The aim of the study was to evaluate markers of exposure to benzene through the exposure biomarker trans, trans-muconic acid (tt-MA), and biomarkers of early renal damage in children who work in sites that are under precarious job conditions. Method: Samples of urine were obtained from children (aged 6–12 years old) who resided in Ticul, Yucatan, Mexico. Exposure to benzene was assessed through trans, trans-muconic acid (t,t-MA). Evaluated renal damage biomarkers were: Cystatin-C (Cys-C), Osteopontin (OPN), α1-Microglobulin (α1-MG) and Neutrophil Gelatinase-Associated Lipocalin (NGAL). Findings: Children who live where the workplace is inside the dwelling presented higher mean levels of tt-MA (0.59 mg/g creatinine) compared with those who live away from the workshops (0.19 mg/g creatinine). Likewise, mean levels of NGAL (4.7, 5.2 ng/ml), albuminuria (10, 10 ng/ml), Cys-C (11.8, 7.5 ng/ml), OPN (224.4, 226.5 ng/ml) and α1-MG (96.6, 73.6 ng/ml) were found in children where the workplace was inside the dwelling and outside, respectively. Conclusion: Our data indicate that the children who work under precarious job conditions are exposed to benzene, and they exhibit protein levels that suggest renal damage in a population in precarious working conditions. Therefore, the child population should be considered as the most vulnerable and susceptible to suffer adverse health effects.

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Background:The World Health Organization (WHO) estimates that 25% of global morbidity and one-third of childhood morbidity may be attributable to environment. Low and high-income countries displayed different environmental risks. Mexico demonstrates the necessity for creating a national environmental health program. In southeastern Mexico, Tixméhuac, is a Mayan community with a high marginalization degree and social backwardness. The main childhood morbidities are acute and chronic diseases.Objective:The aim of the study was to recognize environmental risks for children’s health in Tixméhauc, Yucatan State.Methods:A total of one hundred children under five years old participated. To identify the environmental risks at home, items from the Green Sheet Guidance (WHO), Salamanca General Survey and Environmental Clinical History were used. To know the prevalence of respiratory diseases and asthma, the International Study of Asthma and Allergies in Children (ISAAC) survey was used. Potentially hazardous sites were identified partially using the Methodology for Identification and Evaluation of Health Hazards in Contaminated Sites from the Pan American Health Organization (PAHO).Findings:The low stature of, malnutrition, presence of wheezing and asthma symptoms in children were higher than expected. The suspected cases of parasitosis and vector-borne disease occurred in 50% of the children. Indoor air quality perception was associated with respiratory pathology history; housing quality was related to suspected cases of vector-borne diseases; drinking water quality was linked to suspected cases of parasitosis. Risk areas in the community include agricultural activity, which has led to deposits of empty containers of agrochemicals and electronic waste among solid waste dump.Conclusion:This study presents observed environmental risks to children in a low development country and in developing countries. The community has a low perception of the environmental risk. The need for public health programs reducing risks to children’s environmental health is imperative.

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