Kecemasan pada masa kehamilan apabila sampai tahap kronis berdampak buruk bagi ibu ataupun bagi bayi. Pada ibu dapat menyebabkan arteri uterus berkontraksi, menurunkan blood flow plasenta dan menurunkan suplai oksigen kepada janin sehingga hal tersebut berdampak pada kondisi bayi seperti detak jantung bayi abnormal, meningkatkan kemungkinan bayi lahir prematur, bayi lahir dengan skor psikomotor yang rendah, dan meningkat kelainan pada perilaku bayi. Salah satu terapi non farmakologis adalah terapi mendengarkan murottal Al Quran. Murottal Al Quran memiliki harmoni nada yang memiliki jenis frekuensi dan panjang gelombang tertentu. Saat rangkaian gelombang tersebut sampai pada pendengaran manusia akan memengaruhi sel-sel otak untuk memulihkan keseimbangan dan koordinasi sehingga dapat menurunkan hormon stres dan mengaktifkan endorfin alami (serotonin). Berkaitan dengan hal tersebut, tujuan penelitian ini adalah mengetahui pengaruh mendengarkan murottal Alquran pada tingkat kecemasan ibu hamil. Penelitian ini merupakan penelitian  yang diambil dengan metode systematical review articles (random clinical trial dan quasi experimental) pada kelima jurnal yang telah di-review. Penelitian ini akan dinilai secara PICOS untuk ditentukan sebagai kriteria eligible pada PRISMA dan disajikan dalam bentuk tabel yang sesuai yaitu Populasi (ibu hamil yang mengalami kecemasan yang diukur menggunakan berbagai macam kuesioner kecemasan), Intervention (mendengarkan murottal Al Quran),  Faktor Prognostik, atau Exposure, Comparition (yang tidak diberikan paparan murottal Al Quran atau dibanding dengan jenis musik lainnya), Outcome (penurunan kecemasan ibu hamil). Hasil penelitian menunjukkan dengan mendengarkan murrotal Al Quran dalam tempo yang lambat dan suasana yang tenang dapat menurunkan tingkat kecemasan pada ibu hamil. Harmoni nada dari murottal Al Quran merupakan spiritual music, memiliki panjang audio dengan jenis frekuensi dan panjang gelombang tertentu, menghasilkan suatu getaran yang dapat memulihkan keseimbangan dan koordinasi, mengaktifkan aktivitas gelombang otak sehingga dapat mengontrol pikiran dan jiwa untuk menurunkan kecemasan. Systematical Review: The Effect of Listening to the Murottal Al-Quran on Reducing Anxiety in Pregnant WomenAnxiety during pregnancy when it reaches a chronic stage can develop into depression and stress. This is very bad for the mother and the fetus. For the mother, it can causes the contraction of placental artery and result in limiting oxygenating, reduce placental blood flow and decrease oxygen supply to the fetus. So that it has an impact on the fetus's condition. It can cause an abnormal fetal heart rate, increase the likelihood of a baby being born prematurely, a baby born with a low psychomotor score and increased abnormalities in infant behavior. One of the non-pharmacological therapies is listening to the Murottal Al Quran therapy. Murottal Al Quran has  harmonic tone which has a certain type of frequency and wavelength. When the wave sequence reaches human hearing, it affects brain cells to restore balance and coordination so as to reduce stress hormones and activate natural endorphins (serotonin). The aim of this study is to determine the effect of listening to the Quranic Murottal on the anxiety level of pregnant women. This research is a study that was taken using the original research articles method (RCT and Quasi Experimental) with the research subject pregnant women who have anxiety. This research will be assessed by PICOS to be determined as an Elegibelity criterion in PRISMA and presented in an appropriate table form. The Criterion are Population (pregnant women who experience anxiety), Intervention (listening to murottal Al Quran), Prognostic Factors, or Exposure, Comparition (those who are not given exposure murottal Al Quran or compared to other types of music), Outcome (decreased anxiety of pregnant women). The results showed that listening to the murrotal Al Quran in a slow tempo, and a calm atmosphere can significantly reduce anxiety levels in pregnant women. The harmony of the tone of the murottal Al Quran is spiritual music, has an audio length with a certain type of frequency and wavelength, produces a vibration that can restore balance and coordination, activates brain wave activity so that it can control the mind and spirit to reduce anxiety.

Asthma is considered a global health problem that, if not managed properly, can reduce the sufferers' quality of life. The purpose of the study was to evaluate the quality of life from the perspectives of asthma severity and the asthma control level. A cross-sectional study was conducted from February to June 2018 on asthmatic adolescents aged 12–14 years old in two public junior high schools in Bandung city, Indonesia. The diagnosis, history of asthma,  severity, and asthma control were established based on the National Asthma Guidelines from the Indonesian Pediatric Society, Global Initiative for Asthma (GINA), asthma control test (ACT), and ISAAC questionnaire. Statistical analysis performed using SPSS v.20 with Spearman's rho to determine the significance. The gender distribution of the 98 subjects was almost similar with slightly more girls (51%). The median age was 13±1 years with average ACT, FVC, and PAQLQ(S) total scores of 20±4, 78±16%, and 5.3±1.3, respectively. The domain scores for symptoms, activity limitations, and emotional function were 4.9±1.4, 5.0±1.3, and 5.7±1.1, respectively. There are correlations between the total  PAQLQ(S) score and asthma severity (p<0.001, r=−0.5) and the level of asthma control (p<0.001, r=0.6). In summary, the quality of life has a relationship with asthma severity and the level of asthma control. Asthma management should not only focus on medication but also ways to maintain a good quality of life. KUALITAS HIDUP REMAJA ASMA DAN HUBUNGANNYA DENGAN KEKERAPAN GEJALA DAN DERAJAT KENDALI ASMAAsma masih menjadi masalah kesehatan penting yang jika tidak ditangani baik, asma dapat menurunkan kualitas hidup anak. Tujuan penelitian ini menilai kualitas hidup dan hubungannya dengan kekerapan gejala dan derajat kendali asma. Penelitian cross-sectional ini dilaksanakan dari bulan Februari hingga Juni 2018 pada remaja asma berusia 12–14 tahun di dua SMPN di Kota Bandung, Indonesia. Diagnosis, riwayat asma, kekerapan gejala, dan derajat kendali asma berdasar atas Pedoman Nasional Asma Anak Ikatan Dokter Anak Indonesia, Global Initiative for Asthma (GINA), asthma control test (ACT), dan kuesioner dari ISAAC. Analisis statistik menggunakan SPSS v.20 dengan uji Spearman’s rho untuk menentukan signifikansi. Distribusi gender dari 98 subjek penelitian hampir sama dengan sedikit lebih banyak perempuan (51%). Usia rerata subjek 13±1 tahun dengan skor rerata ACT, FVC, PAQLQ(S) masing-masing 20±4, 78±16%, dan 5,3±1,3. Skor domain gejala, keterbatasan beraktivitas, dan fungsi emosi masing-masing 4,9±1,4; 5,0±1,3; dan 5,7±1,1. Terdapat hubungan skor total PAQLQ(S) dengan kekerapan gejala (p<0,001; r=−0,5) dan dengan derajat kendali asma (p<0,001; r=0,6). Simpulan, kualitas hidup berhubungan dengan kekerapan gejala dan derajat kendali asma. Pengelolaan asma sebaiknya tidak hanya memperhatikan pengobatan, tetapi juga menjaga kualitas hidup yang baik.

Asma merupakan salah satu penyakit tidak menular kronik dari saluran pernapasan paru yang menyebabkan inflamasi dan penyempitan. Asma sering berhubungan dengan gizi lebih dalam pengembangan maupun memperparah penyakit asma. Perubahan pola pernapasan pada penderita gizi lebih dapat menyebabkan volume paru menurun diakibatkan oleh perubahan pada otot polos dan fungsi pernapasan. Penelitian ini bertujuan menganalisis efek gizi lebih terhadap fungsi paru pada anak dengan asma. Penelitian ini menggunakan studi observasional analitik dengan rancangan penelitian kasus kontrol. Variabel bebas dihubungkan dengan variabel terikat dengan analisis statistik uji chi-square. Data diperoleh dengan melakukan wawancara menggunakan kuesioner ISAAC untuk menentukan diagnosis asma anak. Selanjutnya, dilakukan penilaian fungsi paru langsung menggunakan spirometri serta mengukur tinggi badan menggunakan mikrotoa dan berat badan menggunakan timbangan yang hasilnya dirujuk pada grafik Z score WHO untuk mengukur indeks massa tubuh. Penelitian ini dilakukan di SMPN 1 dan SMPN 9 Kota Bandung periode 1 April–25 Mei 2018. Hasil penelitian ini menunjukkan bahwa anak asma dengan gizi lebih mempunyai risiko restrictive ventilatory defect lebih besar 3,4 kali dibanding dengan anak asma dengan gizi normal (OR:3,4; IK95%: 1,4–8,5; p=0,014). Simpulan, anak asma dengan gizi lebih mempunyai efek restrictive ventilatory defect lebih banyak dibanding anak asma dengan gizi normal. THE EFFECT OF OVERNUTRITION ON LUNG FUNCTION IN ASTHMATIC CHILDHOODAsthma is a chronic non-communicable disease of the pulmonary respiratory tract which causes inflammation and constriction. Asthma is often associated with overnutrition in developing or exacerbate asthma. Changes in respiratory patterns in patients with overnutrition can cause lung volume caused by smooth muscle disorders and respiratory function. This study aims to analyze the effects of overnutrition on lung function in children with asthma. This study used observational analytic studies with case control research designs. The independent variable varies with the chi-square test statistical analysis. Data were obtained by conducting interviews using the ISAAC questionnaire to determine the diagnosis of childhood asthma. Furthermore, knowing lung function directly using spirometry also measured height by mikrotoa and weight by the scales that are being referred to the WHO Z score to measure body mass index. This research was conducted at SMPN 1 and SMPN 9 in Bandung City period 1 April–25 May 2018. The results of this study showed that asthmatic children with overnutrition have a 3.4 times greater restrictive ventilatory defect risk than asthmatic children with normal nutrition (OR:3.4, 95%CI: 1.4–8.5, p=0.014). Conclusion, asthmatic children with overnutrition have more restrictive ventilatory defect effects than asthmatic children with normal nutrition.

The prevalence of obesity in asthmatic patient has increased, and associated with worse asthma severity and quality of life. This study investigates the effect of gender and overnutrition on asthma severity. Observational study on 41 overnutrition (overweight and obese), and 41 normweight asthmatic adolescents in two primary high schools. Diagnosis and asthma severity based on GINA, ISAAC and Indonesian Paediatrician Association (IDAI). The BMI was converted to z score from WHO, and lung function was measured by spirometer. The statistical analysis was performed with the software SPSS v.20. The mean BMI in female was higher than male. The mean FEV1; FVC; FEV1/FVC in female was lower than male. The mean FEV1; FVC; FEV1/FVC in overnutrition was lower than normweight. Based on asthma severity: 39% intermittent, 39% mild persistent, 17% moderate persistent, and 5% severe persistent. As many as 77% of 47 females had persistent, of 41 overnutrition asthmatic adolescents 85% had persistent asthma. There are an impact of gender and overnutrition on asthma severity (OR:4.4; 95%CI:1.7-11.3; p=0.002 and OR:9.1; 95%CI:3.1-26.5; p<0.001). Among asthmatic adolescents the risk for persistent asthma was greater in females with overnutrition compare to males.