Stroke is one of non-communicable diseases and affected by many risk factors. Some stroke risk factors have in common with the metabolic syndrome criteria, such as abdominal obesity, glucose intolerance, decreased HDL cholesterol, elevated triglyceride levels, and insulin resistance. The goals to analyze the relationship between the metabolic syndrome with the incidence of stroke. This research is analytic by using case-control design. The case groups were hospitalized patients of stroke and undergoing inpatient in dr. M. Soewandhie Surabaya. The case groups were 32 peoples and control group 32 peoples were selected at random. The variables studied were age, sex, metabolic syndrome, the first criteria, the second criteria of metabolic syndrome, and the third criteria of metabolic syndrome. The results showed that the majority of stroke patients in the age range 51-75 years (78%). Results of Chi-Square test indicates a significant relationship between the metabolic syndrome criteria first (abdominal obesity, triglycerides, and HDL cholesterol levels) p = 0,01 OR = 6,82 (95% CI = 1,23 to 68,17 ) and the second criteria of metabolic syndrome (HDL cholesterol, blood pressure, and fasting glucose levels) p= 0,007 OR = 5,80 (95% CI = 1,30 to 35,15) with the incidence of stroke. While for the third criteria of metabolic syndrome (fasting glucose levels, abdominal obesity, triglyceride  levels) there was no significant relationship to the incidence of stroke. It is expected for people, especially over the age of 35 years can do a lipid profile and circle abdominal measurements to detect of   metabolic syndrome and the risk of stroke.Keywords: Metabolic Syndrome, Stroke, Abdominal Obesity, Triglyceride, HDL

ABSTRAKStroke adalah salah penyakit tidak menular yang dipengaruhi oleh banyak faktor risiko. Beberapa faktor risiko stroke memiliki kesamaan dengan kriteria sindroma metabolik, diantaranya adalah obesitas abdominal, intoleransi glukosa, penurunan kolesterol HDL, peningkatan kadar trigliserida, dan resistensi insulin. Tujuan untuk mengetahui hubungan antara sindroma metabolik dengan kejadian stroke. Jenis penelitian ini adalah analitik dengan menggunakan desain kasus kontrol. Kelompok kasus adalah penderita stroke yang sedang menjalani rawat inap di RSUD dr. M. Soewandhie Surabaya. Kelompok kasus sebanyak 32 orang dan kelompok kontrol sebanyak 32 orang, yang dipilih secara acak. Variabel yang diteliti adalah usia, jenis kelamin, sindroma metabolik kriteria pertama, sindroma metabolik kriteria kedua, dan sindroma metabolik kriteria ketiga. Hasil penelitian menunjukkan bahwa sebagian besar penderita stroke pada rentang usia 51-75 tahun (78%). Hasil uji Chi-Square test menunjukkan adanya hubungan yang signifikan antara sindroma metabolik kriteria pertama (obesitas abdominal, kadar trigliserida, dan kadar kolesterol HDL) p = 0,01 OR = 6,82 (95% Cl = 1,23-68,17) dan sindroma metabolik kriteria kedua (kadar kolesterol HDL, tekanan darah, dan kadar glukosa puasa) p = 0,007 OR = 5,80 (95%Cl = 1,30-35,15) dengan kejadian stroke. Sedangkan sindroma metabolik kriteria ketiga (kadar glukosa puasa, obesitas abdominal, kadar trigliserida) tidak terdapat hubungan yang signifikan dengan kejadian stroke. Diharapkan bagi masyarakat terutama yang berusia di atas 35 tahun bisa melakukan pemeriksaan profil lipid dan pengukuran lingkar pinggang dengan teratur untuk mendeteksi sindroma metabolik dan juga risiko stroke. (abdominal obesity, triglycerides, and HDL cholesterol levels) p = 0,01 OR = 6,82 (95% CI = 1,23 to 68,17) and the second criteria of metabolic syndrome (HDL cholesterol, blood pressure, and fasting glucose levels) p = 0,007 OR = 5,80 (95% CI = 1,30 to 35,15)