A growing body of evidence has revealed that microRNA (miRNA) expression is dysregulated in cancer, and they can act as either oncogenes or suppressors under certain conditions. Furthermore, some studies have discovered that miRNAs play a role in cancer cell drug resistance by targeting drug-resistance-related genes or influencing genes involved in cell proliferation, cell cycle, and apoptosis. In this regard, the abnormal expression of miRNA-128 (miR-128) has been found in various human malignancies, and its verified target genes are essential in cancer-related processes, including apoptosis, cell propagation, and differentiation. This review will discuss the functions and processes of miR-128 in multiple cancer types. Furthermore, the possible involvement of miR-128 in cancer drug resistance and tumor immunotherapeutic will be addressed.
In vehicles that require a lot of electricity, such as electric vehicles, it is necessary to use high-energy batteries. Among the developed batteries, the lithium-ion battery has shown better performance. This battery has an energy density of 10 equal to that of a lithium-ion battery and uses air oxygen as the active material of the cathode and anode like a lithium-ion battery made of lithium metal. The cathode used in these batteries must have special properties such as strong catalytic activity and high conductivity, and nanotechnology has greatly helped to improve the materials used in the cathode of lithium-air batteries. The importance of proper catalyst distribution and the relationship between the oxide product and the catalyst and the indirect effect of the ORR catalyst on the OER reaction is not present in the fuel cell. The maximum capacity of lithium-air battery theory using graphene under optimal electron conduction conditions and the experimental maximum obtained for graphene by optimizing the structure geometry, examples of structural engineering using carbon fiber and carbon nanotubes in cathode fabrication with the ability to perform the reaction properly while providing space for lithium oxide placement, are examined. This article describes the mechanism of this battery, and its components are examined. The challenges of using this battery and the application of nanotechnology to solve these challenges are also discussed.
Here, the magnetic Fe3O4@SiO2/PAEDTC@MIL-101 (Fe) with a new core-shell structure was synthesized, and its sonophotocatalytic properties were evaluated for acid red 14 (AR14) degradation. Particle characterizations were determined by scanning electron microscope (SEM), transmission electron microscopy (TEM), X-ray powder diffraction (XRD), and vibrating-sample magnetometer (VSM), and the analysis results offered an excellent synthesis of mesoporous particles. Fe3O4@SiO2/PAEDTC@MIL-101 (Fe)/UV/US showed high degradation kinetics rate (0.0327 min−1) compared to sonocatalytic processes (0.0181 min−1), photocatalytic (0218 min−1), sonolysis (0.008 min−1), and photolysis (0.005 min−1). Maximum removal efficiencies of AR14 (100%) and total organic carbon (69.96%) were obtained at pH of 5, catalyst mass of 0.5 g/L, initial AR14 concentration of 50 mg/L, and ultrasound power of 36 W. Evaluation of BOD5/COD ratio during dye treatment confirmed that the sonophotocatalysis process can be useful for converting major contaminant molecules into biodegradable compounds. After recycling eight times, the prepared composite still has sonophotocatalytic degradation stability above 90% for AR14. Scavenging tests confirmed that holes (h+) and hydroxyl (•OH) were the pivotal agents in the decomposition system. Based on the results, the synthesized sample can be suggested as an excellent and promising sonophotocatalyst for the degradation of AR14 dye and its conversion into biodegradable compounds.
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