To analyze the efficacy of a complex technology of laser surgery for pigmentary glaucoma which consists of YAG-laser iridectomy in the first stage followed by multistage selective laser trabeculoplasty to achieve a mild pigmentation degree of the trabecula in 360 0 . Materials and Methods:Laser iridectomy was performed in 19 patients (38 eyes) aged 18 to 54 years old with pigmentary glaucoma after achieving the values of the individual IOP level using drug therapy. Then after 4 weeks SLT was carried out. If an exogenous pigmentation was ≥ 2 st., SLT has been repeated several times every 4-6 months. Observation period: from 4 to 15 years. Results:The glaucoma process stabilization was achieved in all cases. The level of true IOP decreased by 6.6 ± 0.3 mm Hg (-30%, p < 0.05), Becker's coefficient by 121 ± 4.3 (-60%, p < 0.001), the instillations number by 0.57 ± 0.09 (-70%, p < 0.001). The indicators increased: the average value of the total retinal photosensitivity by 381 ± 4.3 dB (15%, p < 0.001), the average threshold of the retinal photosensitivity by 2.6 ± 0.1 dB (10%, p < 0.001), the intraocular liquid outflow by 0.08 ± 0.013 (72%, p < 0.001). Drug hypotensive therapy was canceled at 16 eyes (42.1%). Conclusion:The complex method of pigmentary glaucoma laser surgery in the form of YAG-laser iridectomy and the multistep SLT is effective and safe. It may be performed for a decrease of increased ophthalmotonus level to the individual IOP against the background of drug treatment.
To assess the dependence of biomechanical parameters on the initial biometric, keratometric and tomographic parameters of the cornea in healthy patients with different refractions, a retrospective study was performed, which included 173 eyes of 173 healthy patients with different refractions. The study analyzed the correlation between indicators of corneal stiffness, biomechanically compensated intraocular pressure, measured using Pentacam HR and Corvis ST (OCULUS Optikgeräte GmbH; Wetzlar, Germany), true keratometry, anteroposterior eyeball size, corneal thickness in the central optical zone and the age of the patient.As a result of the study, a significant direct dependence of the corneal stiffness parameter was noted, first of all, on the corneal thickness in the central optical zone (p = 0.0000), on the level of biomechanically compensated intraocular pressure (p = 0.0056), as well as a reliable inverse dependence on keratometry (p = 0.0465), but there was no influence on the patient's age (p = 0.382) and the anteroposterior eyeball size (p = 0.851).
Examination and treatment of 50 patients (50 eyes) with the early stage of primary open angle glaucoma before and after application of complex laser surgery technology was carried out. Selective laser trabeculoplasty in combination with YAG-laser trabeculostomy was performed in the projection of the outflow meshwork. Hypotensive effect was 31.1% of the initial intraocular pressure level on the 1 st post-op day and remained for a month after the surgery due to the outflow improvement of the intraocular fluid by 62.5%. The YAG-laser and OCT data allow optimization of YAG trabeculostomy, providing an alternative noninvasive laser treatment for patients with primary open angle glaucoma.
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