To assess the dependence of biomechanical parameters on the initial biometric, keratometric and tomographic parameters of the cornea in healthy patients with different refractions, a retrospective study was performed, which included 173 eyes of 173 healthy patients with different refractions. The study analyzed the correlation between indicators of corneal stiffness, biomechanically compensated intraocular pressure, measured using Pentacam HR and Corvis ST (OCULUS Optikgeräte GmbH; Wetzlar, Germany), true keratometry, anteroposterior eyeball size, corneal thickness in the central optical zone and the age of the patient.As a result of the study, a significant direct dependence of the corneal stiffness parameter was noted, first of all, on the corneal thickness in the central optical zone (p = 0.0000), on the level of biomechanically compensated intraocular pressure (p = 0.0056), as well as a reliable inverse dependence on keratometry (p = 0.0465), but there was no influence on the patient's age (p = 0.382) and the anteroposterior eyeball size (p = 0.851).