Everyday healthcare objects have become the focus of interdisciplinary research lines, which aim to monitor human biomedical parameters by means of ergonomic and, ideally, environmentally sustainable sensors. Here, a hybrid system, based on both solution processed-and conventional silicon-technology, is reported. In particular, a strain and a pH sensor are developed based on graphene inks, whilst a humidity detector is implemented using a poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS). The printed sensors are integrated into a demonstrator consisting of a silicon near field communication (NFC) transponder chip with logic and transceiver capabilities, bonded on a circuit board with inkjet-printed components on a paper substrate: an antenna and a power supply (in addition to the sensor). This proof-of-concept seeks to address the needs for future circular economy, as well as those for cheap, flexible and lightweight, multi-functional electronics.