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During 31 August 2015, Hurricane Fred traversed through the Cape Verde islands, passing near Boa Vista and possibly making landfall over São Nicolau during the evening hours. Hurricane Fred was a category 1 storm with maximum winds of 75 kt and a sea level pressure of 986 hPa during 31 August. The African easterly wave associated with Tropical Cyclone (TC) Fred emerged from Guinea on 29 August and was named Tropical Storm Fred on 30 August. Prior to impacting Cape Verde, the storm caused the sinking of a ship and the loss of seven lives off the coast of Guinea-Bissau and damage along coastal zones of Senegal. In Cape Verde, there was no loss of life but there was damage on 7 of the 10 islands. Station data show tropical-storm-force winds in Boa Vista and Sal and hurricane-force winds in São Nicolau. Heavy precipitation with amounts in excess of 200 mm occurred on the islands of Santiago, São Nicolau, and Santo Antão. The Weather Research and Forecasting (WRF) Model and Global Forecast System (GFS) were used as primary guidance several days prior to the formation of TC Fred. Challenges for protecting populations from tropical cyclones can be addressed through annual hurricane awareness and preparedness programs in several languages. This is also an adaptation strategy related to anthropogenic climate change as warming tropical oceans may increase the risk of damage and threaten populations. Radar and buoy observations are needed now, and the movement of vulnerable populations and other adaptation strategies will need to be implemented in the coming decades.

Hereditary angioedema is an autosomal dominant genetic disease that causes tissue edema mediated by bradykinin. The angioedema attacks have several triggers including stress, trauma, infection, and increased estrogens levels. This explains the greater incidence and clinical severity in women, which are usually asymptomatic until puberty, when the attacks begin to occur. It may involve multiple locations on the body, leading to complications, such as surgical intervention prompt by severe acute abdominal pain, and laryngeal edema that can culminate in death from asphyxia. This is of particular concern as this angioedema does not respond to life-saving medications commonly used in its treatment, namely, high doses of second-generation antihistamines, corticosteroids, and epinephrine. Hereditary angioedema attacks are treated with specific medication that includes icatibant, ecallantide, and C1 inhibitor, the latter being also used in short-term and long-term prophylaxis. There are other pharmacological strategies for long-term prophylaxis like lanadelumab, danazol, stanozolol, aminocaproic acid, and tranexamic acid. During pregnancy and lactation, the preferred treatment and prophylaxis is C1 inhibitor. We report a case of hereditary angioedema describing its chronological evolution over a period of a woman's life, and highlighting some of the specificities of this pathology that intersect with the specialty of Obstetrics and Gynecology. Our aim is to draw attention to these particularities, namely the triggering factors of crisis, the need for high suspicion of the diagnosis, and the treatment and prophylaxis options for pregnant and non-pregnant women that can make the difference between life and death. To achieve a favorable outcome, the multidisciplinary teamwork between the specialties of Immunoallergology and Obstetrics and Gynecology was crucial.

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