From November 1992 to November 1994 stool samples were obtained from 237 children admitted to a public hospital in Belém. Rotaviruses were detected in 19.3 per cent (60/310) of faecal samples. Of these, 32.1 per cent (18/56), 20.9 per cent (38/181), and 5.4 per cent (4/73) were recorded in cases of nosocomial diarrhoea, community-acquired diarrhoea, and controls, respectively. Fifty-two (86.7 per cent) of the 60 rotavirus-positive specimens were subgrouped and the G serotypes of 55 (91.7 per cent) of them were determined. Subgroups I and II were detected in 50 per cent each of the 52 subgrouped strains. G type 2 was present in 46 (83.6 per cent) of the 55 serotyped samples; serotypes G1 and (mixed) G1 and G4 were found in 14.5 per cent and 1.8 per cent, respectively, of these specimens. Viral RNA electrophoresis showed 14 distinct patterns, including 56.7 per cent (34/60) and 43.3 per cent (26/60) of long and short profiles, respectively. In 40 (66.6 per cent) of the 60 rotavirus-positive faecal samples no enteropathogens other than rotavirus were detected. There was an increased incidence of rotavirus infection from July 1993 to February 1994. The rotavirus-related episodes of diarrhoea were more severe than those of other aetiology and greater clinical severity was not related to a specific G type, subgroup, or electrophoretype.
ResumoObjetivo: Verificar a incidência de sífilis congênita em neonatos, em maternidade de hospital público.Métodos: A pesquisa foi realizada na maternidade do Hospital Fundação Santa Casa de Misericórdia do Pará, no período de maio a setembro de 1996. Foram entrevistadas 361 puérperas e realizados os exames físicos de seus recém-nascidos. Ambos foram submetidos a 3 exames sorológicos: VDRL, FTA -Abs, ELISA IgM. Para o diagnóstico de sífilis congênita, empregaram-se os critérios indicados pelo Ministério da Saúde em 1993.Resultados: A incidência de sífilis congênita foi de 9,1% (33); em 14 casos, houve um ou mais sinais indicativos da doença: prematuridade, hepatomegalia, natimortalidade, esplenomegalia, neomortalidade, distensão abdominal, obstrução nasal, icterícia, recém-nascido pequeno para a idade gestacional. A maioria das mães com sífilis estava na faixa de 20 a 35 anos de idade (81,8%); 60,6% eram casadas; 63,6% haviam realizado o pré-natal; 48,5% referiram abortos espontâneos e 12,1% episódios de natimortalidade, em gestações anteriores; 12,1% confessaram consumir drogas. Bissexualidade paterna foi registrada em 9,1% dos casos.Conclusão: Os programas de controle da sífilis e os cuidados pré-natais não estão conseguindo prevenir a incidência expressiva da moléstia.J. pediatr. (Rio J.). 1999; 75(2):119-125: sífilis congênita, recém-nascido. AbstractObjective: To determine the incidence of congenital syphilis among newborns at the maternity of a public hospital.Methods: The study was conducted at the maternity of Fundação Santa Casa de Misericórdia do Pará, from May to September 1996; 361 mothers were interviewed, and physical examination was performed in their newborns. Serum samples from both, mothers and neonates, were tested using three methods: VDRL, FTA -Abs, ELISA IgM. The diagnosis of congenital syphilis was established according to the criteria defined by Ministério da Saúde in 1993.Results: The rate of congenital syphilis was of 9.1% (33); in 14 cases, there were one or more signs of the disease: prematurity, hepatomegaly, stillbirth, splenomegaly, perinatal death, abdominal distention, nasal stuffiness, jaundice, newborn small for gestational age. The majority of the infected mothers belonged to the age group of 20-35 years (81.8%); 60.6% were married; 63.6% received prenatal care; 48.5% reported previous spontaneous abortion, and 12.1% previous stillbirth. The rate of bisexuality among fathers was of 9.1%. Conclusion:The syphilis control measures and the prenatal care, have not been sufficient to prevent the high rate of the disease.J. pediatr. (Rio J.). 1999; 75(2):119-125: congenital syphilis, newborn. IntroduçãoCom o advento da penicilina, diminuiu muito a incidência de sífilis. Porém, o número de casos relatados aumentou a partir de 1980 nos EUA 1 e, atualmente, a sífilis representa sério problema de saúde pública em muitos países, inclusive no Brasil 2 .A sífilis pode ser transmitida ao concepto em qualquer fase da gravidez. A OMS estima em 85,0% a taxa média de transmissão vertical em ges...
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