This study describes the ultrastructure of the taste buds of the sighted river fish Astyanax mexicanus and of the blind cave fish Astyanax jordani (= Anoptichthys) (Teleostei, Characiformes, Characidae). In Astyanax and Anoptichthys, taste buds occur in the epithelia of the lips, oral cavity, and, in Anoptichthys, lower jaw. Both possess three types of taste buds: type I (elevated), type II (slightly elevated), and type III taste buds (not elevated or sunken). The taste buds are up to 60 microm high and up to 35 microm wide. The taste bud's sensory epithelium consists of 100--130 elongated cells: light cells, dense-cored-vesicles (dcv) -cells, dark cells, and degenerating cells. The dcv-cells are rich in dense-cored vesicles and are described for the first time in a teleostean taste bud. At the taste bud's base, there lie two to three basal cells. The basal cells of type I and type II taste buds have microvillus (spine)-like processes, in contrast to those of type III taste buds. The taste bud's nerve fiber plexus is situated between the bases of the elongated taste bud cells and the basal cells. Afferent synapses occur between dcv-cells and basal cells (presynaptic sides) and axons (postsynaptic side). Indistinct synapses occur between light cells and dark cells (presynaptic sides) and axons (postsynaptic side). The nerve fiber plexes of Anoptichthys type II and type III taste buds contain significantly more axon profiles than those of Astyanax. This may be associated with a compensatory improvement of the sense of taste in the blind, cave-dwelling fish.

Taste buds are the peripheral sensory organs of the gustatory system. They occur in all taxa of vertebrates and are pear-shaped intra-epithelial organs of about 80 microm height and 50 microm width. Taste buds mainly consist of specialized epithelial cells, which synapse at their bases and therefore are secondary sensory cells. Taste buds have been described based on studies of teleostean species, but it turned out that the ultrastructure of teleostean taste buds may differ between distinct systematic groups and that this description is not representative of those taste buds in other main taxa of fishes, such as selachians, holosteans and dipnoans. Furthermore, it is not known how variable the micromorphologies of non-teleostean taste buds are. For this reason the taste buds of two holosteans, Lepisosteus oculatus and Amia calva, were investigated and compared. While in both species the taste buds are of the same shapes and sizes, the cellular components of their sensory epithelia differ: in Lepisosteus taste buds comprise two types of elongated light cells and one type of dark cells. In contrast, Amia taste buds contain only one type of light, but two types of dark elongated cells. Afferent synapses are common in the buds of both species, efferent synapses occur only in Lepisosteus taste buds. These differences show that even in the small group of holostean fishes the taste buds are differently organized. Consequently, a representative type of fish taste buds does not exist.

As compared to the general population schizophrenic patients are at increased risk of becoming delinquent. The majority of schizophrenic patients do not commit any crime, and the risk of the general population to be a target of a violent act by a person with schizophrenia is low. The causes of delinquency in schizophrenia are complex, but certain risk characteristics (e. g. an accompanying substance abuse) have been identified. The treatability and legal prognosis of schizophrenic offenders are good, which suggests that establishing a suitable helpers network could also be used for violence prevention in patients at risk.