Background . Few studies have focused on the effects of COVID-19 on African populations. During the first epidemic wave in Senegal (May 1 to July 31, 2020), COVID-19 cases were isolated in treatment centers of epidemics (TCEs). We described the demographics and outcomes of COVID-19 cases in TCEs. Patients and Methods . All cases with laboratory-confirmed COVID-19 in Thiès medical region of Senegal were included. Results . COVID-19 was confirmed in 600 cases. Median age of cases (men: 357, 59.5%; women: 243, 40.5%) was 34.0 years. The incidence was 12 per 100,000 inhabitants per month. Overall, 46 (7.7%) cases had a severe or critical form of the disease, and nine of them died. Of 455 cases quarantined in non-hospital TCEs, 340 (74.7%) had no symptom and 115 (25.3%) had mild or moderate symptoms. Conclusion . In this African retrospective cohort, COVID-19 cases were young and mostly asymptomatic with a low case fatality rate.

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De nombreuses études ont démontré que les femmes infectées par le VIH ont un risque accru de survenue de néoplasies cervicales intra épithéliales. L'association entre les deux affections étant bidirectionnelle, l'objectif était de décrire les anomalies cervicales chez les femmes séropositives au virus de l'immunodéficience humaine (VIH), de rechercher des facteurs associés et de proposer des recommandations en termes de suivi de ces femmes. Il s'agissait d'une étude transversale, multicentrique recensant l'ensemble des frottis cervico-vaginaux (FCV) et des colposcopies des patientes infectées par le VIH entre 2012 et 2014 dans les services de dermatologie de Thiès et de Mbour. Les données étaient recueillies et analysées par le logiciel EPI Info 2012 version 3.5.4. Les tests statistiques ont été effectués avec un seuil de significativité p <0,05. Etaient inclus 125 patientes. L’âge moyen était de 38,98 ± 10.2 ans [20-77]. Il n'y avait aucun signe d'appels dans 82.4%. Le FCV était normal dans 32.8%, inflammatoire dans 44.8%. Les anomalies cytologiques concernaient 22,4% dont, ASC-H (suspicion de lésions de haut grade: 2.4%), LSIL (lésions de bas grade: 8.8%), HSIL (lésions de haut grade: 4%). Leur majorité (60.7%) avaient un taux de CD4 < 500 et étaient au stade 3 de l'OMS dans 64.3%; la biopsie montrait une dysplasie sévère chez 37.5% des patientes ayant pu réaliser cet examen. Deux patientes ont bénéficié d'un traitement curatif notamment l'exérèse chirurgicale. La survenue de dysplasies cervicales même précoces semble être associée à un stade avancé de l'infection VIH. Un dépistage et un traitement précoces sont absolument nécessaires.

New Coronavirus Disease (SARS-CoV-2) is responsible for the severe acute respiratory syndrome. Appeared in Wuhan, China, in December 2019, it affects more than 188 countries around the world to date. Africa is not spared by this pandemic (COVID-19), which is on the rise. Tuberculosis (TB), a disease endemic in Africa with a fatality of 1.5 million people per year , like COVID-19, is transmitted mainly by the respiratory route and affects the lungs[1,2]. In the literature, few studies have demonstrated the association and interactions between these two pathologies. However, the fragmented data reveal that tuberculosis with pulmonary localization must be considered as a potential risk factor for aggravation or complication of the disease. COVID-19, especially since the lung damage is significant, therefore In the fight against the COVID-19 pandemic, we must not forget to suspect and appropriately manage tuberculosis [2]. We report here the case of 3 patients who presented with COVID-19-Tuberculosis co-infection, treated at the level of the Epidemic Treatment Center (CTE) of the Thiès regional hospital in Senegal and whose evolution is favorable under early and adequate treatment.

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