No abstract

During the last 15 years, seventeen patients with polypoid lesions or carcinoma in the colon or rectum were repeatedly examined with barium enemas. The doubling time of these colorectal tumors was calculated according to Spratt's theory of the growth rate of neoplasms. The doubling times of 6 carcinomas varied from 92.4 to 1032.2 days with those of early carcinomas being much shorter than those of advanced lesions. Advanced lesions of the proximal colon had a shorter doubling time than those of the distal colon. The doubling times of 6 adenomatous polyps ranged from 146.5 to 398.5 days, thus coinciding with the time interval of the carcinomas. However, 5 other adenomatous polyps did not grow during the follow-up period which ranged from 420 to 816 days. There was no definite correlation between the doubling time and the histology of the tumors. The difference in the doubling time of carcinomas correlated more with location than the histological grade of malignancy.

Endoscopic examination using a specially designed sonde-type small intestinal fiberscope (SSIF, Olympus) was performed in 37 patients of our clinic. The improvement of the scope has enabled us to observe the greater parts of the small intestine within a short time and without hazard to the patient. Therefore, with further improvement of this instrument and the insertion technique, we will be able to inspect all parts of the small intestinal mucosa and diagnose the lesions more easily.

We divided the erosive gastritis into two types, namely, the mature type and the immature type. The mucosal elevation consisted of fibrosis in the former type and of edema in the latter. The surrounding mucosal elevation is irreversible in the erosive gastritis of mature type, on the contrary, it is reversible in the immature type. It is difficult to differentiate these two types, however, it is possible by the repeated examination. The frequency rate of the erosive gastritis is hard to evaluate, however, taking into consideration the factors, gastric juice, allergic reaction, and auto-immune mechanism for the development of the erosive gastritis; we must think over the "Erosion". The frequency rate of the erosive gastritis is high in the case of gastric and duodenal ulcer, the differentiation of the erosive gastritis from the flat erosion will be greatly suggestive for the diagnosis and treatment of the ulcerative lesion.Endoscopy 3 (1970) 168-174

Among the duodenal lesions, the duodenal ulcer was most frequently observed. The patients were 10 years younger on the average than those with gastric ulcer. Concerning the sex of the patient, male was more dominant than female.Single duodenal ulcer was most frequently observed on the anterior wall, less often, on the posterior wall. 3. 137 cases of single duodenal ulcers were observed: 99 of them were round, 25 linear, 9 irregularly shaped and 4 cases were of the "Salami" type. 4. In 22 cases of multiple duodenal ulcer, 20 cases were kissing between on the anterior wall and on the posterior wall, and 2 cases were irregularly arranged. 5. Investigating the relationship between the radiological diagnostic ability with the endoscopical one, the duodenofiberscope was proved to be more useful and more reliable for any diagnosis of location, number, shape or stage of duodenal ulcer than the radiological findings. Particularly for determination of the stage of a duodenal ulcer, active or healed, the duodenofiberscope should be used. 6. The correlation could be demonstrated between the deformity of duodenal cap and the duodenal ulcer. Namely, in 96°/o of duodenal ulcers, a deformity of the duodenal cap could be observed, and the degree of deformity was higher in the multiple ulcers than in the single ones, and also in the linear ulcers than in those of other shape.