In spite of the large utilization of LiNb0 3 in optical devices, its electro-optic coefficients are not perfectly known. We show in the present paper that not taking into account the temperature dependence of the linear spontaneous birefringence can lead to an erroneous determination of the electro-optic coefficients. The electro-optic coefficient rc of LiNb0 3 has been determined by an accurate technique issued from the Senarmont methodo At room temperature, Y c = 19.9 X 10-12 m/V, with an estimated error of ± 5%. The measurements are performed for values of the de applied electric field as a function of the temperature around room temperature. We point out the drastic influence on the electro-optic response of the spontaneous birefringence variation due to the temperature. Accurate and reproducible values of the electro-optic coefficients are obtained only if this dependence is taken into accounto
A novel system is presented which is capable of measuring with high accuracy the linear (Pockels) electro-optic effect by means of a new dynamic (ac) method. This method is based on the observation of the photodetected output obtained from a Senarmont-type ellipsometric system with an ac (modulating) voltage being applied onto the electro-optic sample under test. This observation is made on a high sensitivity oscilloscope and allows us to determine accurately the null point of the system by locating the position of the analyzer that produces in the output a characteristic and abrupt doubling of the (modulation) frequency. By locating this frequency doubling position without and with electric field one can finally determine the corresponding electro-optic coefficients. Theoretical analysis and considerations of practical interest are presented in the article and show that the system in question can ensure reduced errors and increased sensitivity. Also, experimental evidence in support of the expected performance is obtained by implementing and applying the system for the measurement of the composite electro-optic coefficient rc of LiNbO3 for various temperatures in the range of 17–20 °C.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Activating mutations in tyrosine kinase receptors KIT or platelet-derived growth factor receptor alpha (PDGFRA) are the main mechanisms causing the disease. Patients generally present with non-specific symptoms, while a number of tumors are discovered incidentally and may be metastatic at the time of diagnosis. Aggressive GISTs have a defined pattern of metastasis to the liver or throughout the abdomen, or both. Though GISTs rarely present systemic or isolated paraneoplastic reactions, a few cases have been reported in the literature. We present the case of a 54-year-old patient with metastatic GIST at diagnosis and the emergence of paraneoplastic manifestations during follow-up.
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