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Campomelic dysplasia (CD) is a rare skeletal dysplasia. The incidence, reported in the literature, is 0.05-0.09 per 10,000 live births. During the period December 1985-December 1990 there were 18,350 live births with 4 cases of CD at Aker University Hospital in Oslo, Norway. This gives an incidence of CD in our observation period of 2.2 per 10,000. Eliminating our first case, because of Pakistani decent, the total incidence is 1.6 per 10,000 among Norwegian infants which is much higher than the incidence previously mentioned. Perhaps CD is under-reported and a high proportion of patients remain undiagnosed. We present four cases and discuss the incidence.

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Effective renal plasma flow (ERPF) and renal venous renin activity (RVRA) were determined for the two kidneys separately before and after intravenous administration of dihydralazine in 50 cases of suspected unilateral renovascular hypertension. A ratio above 1.4 between the ERPFs of the two kidneys and an RVRA ratio above 1.5 were used as signs of lateralization. The two procedures showed agreement about presence or absence of lateralization in 36 cases before and 44 after dihydralazine administration. Eleven patients underwent surgery. ERPF and the changes in ERPF induced by dihydralazine gave important prognostic and preoperative information. Data on renin release rates are presented.