Purpose -In microfluidic channel fabrication in low temperature co-fired ceramics (LTCC), one of the biggest challenges is the elimination of channel deformation during lamination. The purpose of this paper is to describe the expected deformation of the substrate and the sacrificial layer (starch powder and 3D printed UV polymerized material) during the lamination process of microfluidic structure fabrication. Design/methodology/approach -Uniaxial compression and Jenike shear test were used to obtain the mechanical parameters of starch sacrificial volume material (SVM). To determine the stress-strain characteristics of LTCC a uniaxial compression experiment was conducted. The shape of the laminated LTCC containing embedded channel was modeled by finite element method using the mechanical parameters obtained by the measurements. Findings -It was found that the choice of SVM plays an important role in channel deformation. A design rule is given considering the channel width and the choice of SVM based on the simulation results. Originality/value -Until now the lamination step of LTCC technology was only optimized in an empirical way.

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The following work introduces a method to carry out patient specific implant design based on computer tomography (CT) imaging technique. Point cloud bone model and the solid model creation process is described in detail. Using the radiodensity level of the CT-scan the continuous distribution of the elastic properties of the bone is also been recorded and used for the material model of the finite element procedure. For this purpose, a continuous mass density – elastic modulus curve is suggested, based on previous results in the literature. Stress shielding poses a serious issue regarding the survival of an implant. Strain energy density (SED) is a good indicator of the effects that drive the remodeling. Based on local SED difference caused by the implant this phenomenon can be quantified and visualized. This makes it possible to classify or redesign the implant in order to minimize the potential bone loss caused by the altered stress state.