Fifteen general practitioners conducted a randomized, double-blind comparative trial of two cerumenolytics, namely, Otocerol and Cerumol. A total of 106 patients were entered into the study (fifty-three in each group). Otocerol was shown to be marginally better than Cerumol in all parameters evaluated.

,ug/ml; higher concentrations of tobramycin were present in urine. Tobramycin proved to be an effective antimicrobial in these patients.

In a pilot study in general practice, using a double blind cross-over technique, twenty-six patients with menorrhagia were treated with Dicynene (ethamsylate) or a placebo preparation during four menstrual periods, each preparation being given for two consecutive periods.The number of tampons used and number of days of menstrual loss were recorded together with the patient's assessment of the severity of bleeding.On statistical analysis the results demonstrated the superiority of Dicynene over placebo in reducing the amount and duration of bleeding in menorrhagia.Twenty-five patients reported an absence of side-effects during the trial. Slight indigestion was recorded in one patient during Dicynene treatment.

No abstract