Chronic undernutrition causes reduced growth and endocrine adaptations in order to maintain basic life processes. In the present study, the biochemical profiles of chronically undernourished children were determined in order to test the hypothesis that chronic undernutrition also causes changes in lipid profile in pre-school children. The study population comprised 80 children aged between 12 and 71 months, including 60 with moderate undernutrition [height-for-age Z (HAZ) scores ≤ −2 and > −3] and 20 with severe undernutrition (HAZ scores ≤ −3). Socioeconomic, demographic and environmental data were obtained by application of a questionnaire, and anthropometric measurements and information relating to sex, age and feeding habits were collected by a trained nutritionist. Blood samples were analysed for haemoglobin, vitamin A, insulin-like growth factor 1 (IGF-1) and serum lipids, while cortisol was assayed in the saliva. Faecal samples were submitted to parasitological investigation. Analysis of variance and χ 2 methods were employed in order to select the variables that participated in the multivariate logistic regression analysis. The study population was socioeconomically homogeneous, while the lack of a treated water supply was clearly associated with the degree of malnutrition. Most OPEN ACCESS Int. J. Environ. Res. Public Health 2010, 74140 children were parasitised and anaemia was significantly more prevalent among the severely undernourished. Levels of IGF-1 decreased significantly with increasing severity of undernutrition. Lipid analysis revealed that almost all of the children had dyslipidemia, while low levels of high-density lipoprotein were associated with the degree of undernutrition. It is concluded that chronic malnutrition causes endocrine changes that give rise to alterations in the metabolic profile of pre-school children.

Objectives: to assess the efficacy of mussels (Mytella falcata) in malnourished children’s recovery. Methods: 64 chronically malnourished children were accompanied for 12 months and attended at the Centro Recuperação e Educação Nutricional (Recovery Center and Educational Nutrition). The children were paired by age and malnutrition level forming three groups, which they received a balanced diet for nutritional recovery differing only on protein source. The group was offered (1) preparation of red meat, group (2) preparation of mussels and group (3) preparation of mussels in coconut milk. Results: the anthropometric assessment revealed that the children obtained a mean increase in the Z score in A-I indice of 0.70 for the group who red meat, 0.62 for the group who had mussels and 0.57 the group who had mussels cooked in coconut milk (p<0,05). An observation was made on a reduction in the prevalence of anemia with 22,8% (p=0,002), 27.8% (p=0.,007) and 42.4% (p 0.001) in groups 1, 2 and 3, respectively. Conclusion: the preparation of mussels cooked in or not in coconut milk can be an effective substitution for meat in combating child malnutrition and anemia and may be included in the children's institutions menus and in the programs that aim for children’s nutritional recovery.

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Objective: To assess the relationship between the sense of coherence (SOC), eating behavior and nutritional status. Design: It is a systematic review Setting: The following databases were searched: MEDLINE/PubMed, Science Direct/Elsevier, LILACS/Bireme, SciELO and Google Scholar, using the indexed terms’ salutogenesis', 'sense of coherence', 'nutritional status', 'nutrition', 'eating behavior’ and 'healthy eating'. The indexed terms were used in Portuguese and English according to the database searched. The data were extracted in a standardized way and the quality of the studies was assessed using the Newcastle-Ottawa scale. Participants: Observational studies were included, with no limitations on the date of publication or language. Results: After reading the titles and abstracts of 1855 articles, 107 full-texts were retrieved, of which 27 were included. Of these, 25 were cross-sectional and 2 were longitudinal. The average score for Newcastle Ottawa studies was 6 and most studies were rated as moderate and low quality. The cumulative sample size of all included studies was 28,981 adults and the elderly, aged between 18 and 81 years. The studies were carried out in 15 different countries. Fifteen articles assessed eating behavior/habit and 12 assessed nutritional status. Studies have shown that SOC has a positive relationship with an appropriate eating behavior/habit. On the other hand, the relationship between SOC and nutritional status was controversial among studies. The heterogeneity of the data resulting from the use of different methods of evaluation of the outcomes of interest (nutritional status and eating behavior) made it impossible to perform a meta-analysis. Conclusion: SOC was positively associated to adequate eating behavior. However, it was not possible to establish a relationship between SOC and nutritional status.