The current body of research on Asian–American mental health issues has not sufficiently addressed the needs of Asian Indians. Demographically and historically this group is distinct from other Asian immigrant groups. This article examines how the unique aspects of Asian Indian culture may differentially impinge on mental health issues such as acculturation, rates of psychopathology, and manifestation of psychiatric symptoms. The ramifications of these factors for the construction of community mental health models for these groups are also addressed. Recommendations and hypotheses for future research in this area are suggested.