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Heat transfer enhancement and design innovation of thermal devices are needed to accommodate growth in heat duty from avionics, electric propulsion, environmental control, and engine systems of current and future aircraft. Additive manufacturing (AM) technology enables exploration of new heat transfer surfaces and complex flow passage geometries to achieve the higher convective heat transfer rates, while minimizing pressure loss, and compactness needed for next generation thermal devices. Effective use of these innovative designs requires the development of new thermo-hydraulic design databases, which include variations in heat exchanger geometries due to the influence of AM processes. The present work deals with performance evaluation of AM-enabled sinusoidal wavy heat transfer surfaces by 3D conjugate heat transfer analysis using Computational Fluid Dynamics (CFD). Numerical simulations were carried out for two thermal boundary conditions consisting of constant wall temperature and constant heat flux in laminar and turbulent flows with a Reynolds number range of 300 to 5000 for varying fin geometry parameters. Numerical results are validated with available literature data and presented in terms of isothermal friction factors and Nusselt numbers. Variation in local heat transfer coefficients and temperatures are discussed to gain insights into the fluid flow and associated heat transfer mechanisms. The parametric study on channel waviness showed that a decrease in wavelength resulted in a relatively large increase in friction factor relative to growth in Nusselt number, which was addressed by rounding of the flow channel corners.