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Background: Although the classic Reed-Sternberg (RS) cell is considered a diagnostic of Hodgkin's disease, RS-like cells have been noted in various benign and malignant conditions. The presence of these cells can be a diagnostic challenge. Aims: Our aim was to see if cells morphologically resembling or identical to RS cells occur in conditions other than Hodgkin lymphoma (HL) and what proportion of cases show binucleate cells in various benign and malignant conditions. We also want to discuss the diagnostic utility of cytomorphological features in predicting HL. Material and Methods: This study is a retrospective analysis of 2086 cytology cases. The cytosmears were screened for the presence of binucleate cells. A detailed cytomorphological analysis of cytosmears with binucleate cells was performed, and the diagnostic utility of cytomorphological criteria in delineating HL was examined. Results: Out of 2086 smears, 55 (2.6%) cytosmears showed binucleated RS/RS-like cells. Out of these 55 cases, 6 were HL, 3 cases were non-HL (NHL), 3 were sarcoma, 32 were carcinoma, and 11 were benign/inflammatory lesions. The presence of prominent eosinophilic nucleoli, granulomas, and eosinophils had good sensitivity and specificity in predicting the diagnosis of HL. Conclusion: A detailed cytomorphological analysis is of limited value in categorizing the RS and RS-like cells. However, few cytomorphological features such as prominent eosinophilic nucleoli, eosinophils, granulomas, and lack of clustering of atypical cells can help us in predicting HL.

Background: Preservation of extraction site with grafting shall always produce better healing results. Various materials have been used for this process and each material has its unique benefits and properties. Few such materials are Simvastatin, Bone ceramic, oxidized cellulose, bone allograft, etc. In this given study, 10 patients were placed Human amniotic membrane in their extracted socket and the results were reviewed after 7days, 14 days, 21 days, 1 month, 3 month and 6 month. Materials and Methods: The samples are voluntary and those patients with no clinical abnormalities were included. Human amniotic membrane is received from Tata Memorial Hospital, Mumbai. Ten patients who reported to Department of OMFS were selected for the augmentation procedure. After extraction, the Human amniotic membrane was placed in the extracted socket and secured with sutures. Post-operative visits scheduled after 7days, 14 days, 21 days, 1 month, 3 month and 6 month intervals for analyzing the he.0aling property of amnion in the augmented extraction sockets. Results: The results of this study have shown that Amniotic membrane has proven its effect, as it initiates faster wound healing of the extraction socket. Conclusion: This article shall reveal the effectiveness of the Human amniotic membrane in rapid wound healing of the augmented extraction socket.