The APS Journal Legacy Content is the corpus of 100 years of historical scientific research from the American Physiological Society research journals. This package goes back to the first issue of each of the APS journals including the American Journal of Physiology, first published in 1898. The full text scanned images of the printed pages are easily searchable. Downloads quickly in PDF format.

The time course and magnitude of delayed compliance in a typical large vein, the external jugular vein of the dog, were studied in an effort to determine whether or not delayed compliance in the large veins is an important factor in allowing the circulatory system to accommodate to large changes in blood volume. These studies showed that essentially all delayed compliance is complete within approximately 20 min and that its magnitude was only one-third to one-fifth as great as the immediate elastic compliance of the vessel. Therefore, it was concluded that delayed compliance in the large veins plays little role in allowing the circulatory system to accommodate itself to large changes in blood volume, and that most of this accommodation must occur in other vascular beds.

No abstract

Dogs under chloralose anesthesia show augmented reflex responses of systolic arterial pressure, mean arterial pressure, diastolic arterial pressure, and pulse rate to bilateral occlusion of the common carotid arteries over the responses of these same parameters before any anesthesia. Hyporeflexia, as indicated by these parameters, is observed when the anesthetic is chloralose and urethan, pentobarbital, or thiobarbital. Less variance in the responses as a result of alteration of the anesthetic level is observed with chloralose or pentobarbital anesthesia than with chloralose and urethan or thiobarbital anesthesia. If either chloralose or pentobarbital is to be used in studies involving the carotid sinus reflex, due consideration must be given to the 8% increase in response of mean arterial pressure under chloralose anesthesia as well as the 9% decrease in response of this same parameter under pentobarbital anesthesia.