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Abstract-In this paper, we propose an Internet of Things (IoT) system application for remote medical monitoring. The body pressure distribution is acquired through a pressure sensing mattress under the person's body, data is sent to a computer workstation for processing, and results are communicated for monitoring and diagnosis. The area of application of such system is large in the medical domain making the system convenient for clinical use such as in sleep studies, non or partial anesthetic surgical procedures, medical-imaging techniques, and other areas involving the determination of the body-posture on a mattress. In this vein, a novel method for human body posture recognition that consists in providing an optimal combination of signal acquisition, processing, and data storage to perform the recognition task in a quasi-real-time basis. A supervised learning approach was used to build a model using a robust synthetic data. The data has been generated beforehand, in a way to enhance and generalize the recognition capability while maintaining both geometrical and spatial performance. Low-cost and fast computation per sample processing along with autonomy, make the system suitable for long-term operation and IoT applications. The recognition results with a Cohen's Kappa coefficient κ = 0.866 was satisfactorily encouraging for further investigation in this field.