A woman presented at the gynecological emergency clinic with severe lower abdominal pain. Even though she reported normal menses and had no risk factors for ectopic pregnancy, pregnancy test was positive and vaginal sonogram indicated heterotopic pregnancy at 12 weeks of gestation, with rupture of the ectopic pregnancy. Laboratory results indicated significant blood loss, and emergency laparotomy with salpingo-ophorectomy was performed. The intrauterine pregnancy continued uneventfully. Interestingly, the previous month the patient had also undergone investigation for vague abdominal pain and anemia. This case, apart from being very interesting because of the rarity of naturally occurring heterotopic pregnancy, shows how a number of factors in patient management and investigation, when combined with rare and uncommon conditions, can lead to incorrect diagnosis with the associated implications for patient safety. This case therefore demonstrates the need for improved patient care and outcome.
Background: Fine needle aspiration cytology (FNAC) has been and still is challenged about its role in the management of breast lesions. Guidelines today mandate that breast lesions should be managed with a triple assessment system consisting of clinical, radiological, and pathological evaluation.
Aim: This article will try and clarify whether FNAC stands as a tool in this assessment.
Materials and methods: PubMed was searched for articles concerning prospective, retrospective and review studies about clinical applications of FNAC.
Results: Specialists agree and evidence occurs that FNAC could be the examination of first choice in matters of pathological evaluation.
Conclusions: It is an easily performed, patient-friendly and cheap examination. It can successfully and quite quickly filter out benign breast conditions without any further cost or stress to the patient. In cases with inconclusive results or insufficient samples it should be followed by needle core biopsy (NCB). As a method, it has its limitations. It cannot directly provide information about tissue architecture, and identify certain breast conditions. Modern developments in liquid based cytology (LBC) upgrade its role in neoadjuvant chemotherapy too. In order to have satisfactory results, high levels of experience are required.
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