Gerd-Martin Rappen scite author profile

Gerd-Martin Rappen

4Publications

36Citation Statements Received

118Citation Statements Given

How they've been cited

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126

118

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Publications

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Dissolution of mesalazine modified release tablets under standard and bio-relevant test conditions

Garbacz¹,

Rappen²,

Koziolek

2015

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The study demonstrates that besides the investigation of the pH dependency of drug release, the characterisation of the mechanical robustness of the dosage forms is an essential factor determining the dissolution characteristics of such pH-dependent targeted modified release tablets. The susceptibility of 800 mg mesalazine MR tablets towards mechanical stress may be one reason for undesired drug delivery in vivo.

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An understanding of modified release matrix tablets behavior during drug dissolution as the key for prediction of pharmaceutical product performance – case study of multimodal characterization of quetiapine fumarate tablets

Kulinowski

Woyna-Orlewicz

Rappen³

et al. 2015

International Journal of Pharmaceutics

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Multimodal approach to characterization of hydrophilic matrices manufactured by wet and dry granulation or direct compression methods

Kulinowski

Woyna-Orlewicz

Obrał

et al. 2016

International Journal of Pharmaceutics

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Controlled release of acidic drugs in compendial and physiological hydrogen carbonate buffer from polymer blend-coated oral solid dosage forms

Wulff

Rappen²,

Koziolek

et al. 2015

European Journal of Pharmaceutical Sciences

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