Die Synthese des dem 2,6‐Di‐(α‐pyridyl)‐pyridin entsprechenden 2,4‐Di‐(α‐pyridyl)‐thiazols wird beschrieben.

Cell extracts of Saccharomyces cerevisiae and Candida guilliermondii catalyze the hydrolytic deamination in position 2 of 2,5-diamino-6-hydroxy-4-ribitylaminopvrimidine 5′-phosphate. The deaminase activity is absent in rib 2 mutants of S. cerevisiae. These findings confirm the biosynthetic pathway proposed earlier on the basis of metabolic and genetic studies [2].

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