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Aim: A novel design for non-reversible as well as reversible parity generator and detector in Quantum-dot Cellular Automata (QCA) technology is presented in this research article. Parity generator and detector circuits are reliable error-checking components of a nano-communication system. Objective: The main focus of this research is to design an ultra-low-power fault-tolerant reversible gate implementation of the parity logic function in QCA. An efficient QCA design layout with minimal area, less latency and the least energy dissipation is desired. Methods: The proposed designs are developed using Quantum-dot Cellular Automata (QCA) technology. The circuits are optimized using majority gate reduction and clock zone reduction techniques. Also, the cell-cell interaction technique is employed to further optimize the QCA circuit. To increase the fault tolerance and for ultra-low power operation, reversible QCA circuits are designed using cascaded Feynman gates. Results and Conclusion: The efficiency of the parity generator and detector is calculated to be more than 25% compared to existing QCA layouts. It is demonstrated in this paper that the proposed circuits perform exceptionally well on every design parameter. The design parameters under consideration are cell count, cell area, complexity, crossover count, latency and energy dissipation. Using reversible logic, a fault-tolerant and defect-sensitive circuit is developed for parity generation and detection.