The first two-dimensional (2D) substance sparked a boom in research since this type of material showed potential promise for applications in field sensors. A class of 2D transition metal nitrides, carbides, and carbonitrides are referred to as MXenes. Following the 2011 synthesis of Ti3C2 from Ti3AlC2, much research has been published. Since these materials have several advantages over conventional 2D materials, they have been extensively researched, synthesized, and studied by many research organizations. To give readers a general understanding of these well-liked materials, this review examines the structures of MXenes, discusses various synthesis procedures, and analyzes physicochemistry properties, particularly optical, electronic, structural, and mechanical properties. The focus of this review is the analysis of modern advancements in the development of MXene-based sensors, including electrochemical sensors, gas sensors, biosensors, optical sensors, and wearable sensors. Finally, the opportunities and challenges for further study on the creation of MXenes-based sensors are discussed.
Cancer is a multifaceted disease that results from the complex interaction between genetic and environmental factors. Cancer is a mortal disease with the biggest clinical, societal, and economic burden. Research on better methods of the detection, diagnosis, and treatment of cancer is crucial. Recent advancements in material science have led to the development of metal–organic frameworks, also known as MOFs. MOFs have recently been established as promising and adaptable delivery platforms and target vehicles for cancer therapy. These MOFs have been constructed in a fashion that offers them the capability of drug release that is stimuli-responsive. This feature has the potential to be exploited for cancer therapy that is externally led. This review presents an in-depth summary of the research that has been conducted to date in the field of MOF-based nanoplatforms for cancer therapeutics.
High-sensitivity biomedical sensors could make it possible to detect and classify chemical and biological species in a variety of applications, from disease diagnosis to medication discovery, thus, boosting the likelihood of life-saving intervention. Synthesized nanowires have already produced advancements in a variety of sectors, including biological sensors over the last decade. When compared to macro-sized materials, the nanowires’ large surface area-to-volume ratio increased sensitivity. Their applications for biomarker, viral, and DNA detection, as well as drug discovery, are also discussed. Self-powering, reusability, sensitivity in high ionic strength solvents, and long-term stability are all examples of recent developments. Shortly, the nanowire is likely to lead to major improvements in biomedical sensors. This review provides a full overview of the nanowire sensor’s working principle and production procedure. We have discussed how to produce nanowires that can be utilized as biosensors for different bacteria and pathogens, protease, DNA and RNA, neurotransmitters, and chemical compounds. Biosensing technology has dramatically improved because of the introduction of nanowires in biosensors. This is a result of the application of new biorecognition components and transducers, improvements in the manufacture, design, and miniaturization of nanostructured devices at the micron scale, and unique approaches for the synthesis of nanowires. The versatility, robustness, and dynamic nature of sensing technologies have all improved thanks to the usage of nanowires.
According to recent studies, interest in metal−organic frameworks (MOFs) and their derivatives are still developing in the field of electrochemical biosensing. This is due to their superior electrical conductivity, active surface area, and easier manufacturing procedures, when compared to other conventional materials. This study discusses current advances in the use of MOF nanoparticles as highly conductive substrates in electrochemical biosensing. Electrochemical biosensing is introduced by categorizing biosensors into enzyme and nonenzyme biosensors and for diagnosis of diseases is based on the application of the active detector. This study systematically compiled and analyzed the most recent published works in each category. This Review provides an overview of the many types of analyses, MOFs materials, and sensor performance. In this subject of science, broad concerns, difficulties, and future views are discussed.
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