(1) Background: homeless people are characterized by serious social vulnerability and difficulty in accessing health services worldwide. In Brazil, this population is supported by the Street Clinic teams who are challenged to establish intersectoral networks to expand access and promote unique and humanized care from the perspective of harm reduction. The study aimed to analyze the practices of professionals working at the Street Clinic in a city in the interior of São Paulo, Brazil, to tackle the vulnerabilities of the homeless population and expand access to the health care network. (2) Methods: a qualitative study was conducted with a social approach in which we interviewed eight workers from the Street Clinic. Data were analyzed using the thematic content analysis tool. (3) Results: three nuclei of meaning were built: stigma and prejudice as the main barriers to accessing services, harm reduction as a humanized care practice and valuing autonomy, and Street Clinic as a gateway to the health system and main interlocutor with other services. (4) Conclusions: the articulation with network services is marked by contradictory relationships, of conflict and trust, signaling the need for greater investment in educational qualifications and working conditions for professionals at all levels of care to expand access to health care.

Objective: to unveil the perceptions of the Street Clinic nursing staff about coping with vulnerabilities. Methods: qualitative study, carried out by means of participant observation of the team’s activities, recording in a field diary and semi-structured interviews with the nursing team, totaling 17 participants. Results: situations experienced by people living on the streets that deepen health inequities by violating rights were revealed. Among the nursing work tools, the potential of collaborative work, listening, and welcoming technologies stand out as mediators of a more humanized care. There is a need for specific strategies to guide nursing care on the streets. Conclusion: nursing has great potential for addressing the vulnerabilities of the homeless population using soft and soft-hard technologies.

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Background The Street Clinic was created to expand access to health for Homeless Persons. Within the service, the role of the nursing team is very important in accessing and establishing care, welcoming, bond building, promoting a save environment, health prevention and education, interdisciplinary communication, patient management and articulation with other services. The research aimed to analyze the objects, instruments, purposes and products in the nursing work process, considering the principle of equity of Brazilian National Health System and the serious vulnerability of the population in question. In this way, it is necessary to understand the valorization of nursing. Methods Study of qualitative approach with participant observation, field diary, application of three semi-structured interviews and use of thematic content analysis method. The study scenario was the nursing team of the Street Clinic in a city in the interior of São Paulo. Results The following elements of the nursing work process were analyzed: dwelling place, health demands and intersectionality of this population (objects); team organization, materials, harm reduction, communication with the intersectoral network, assistance, health guidance, opportunities for action, administration, management and personal and professional transformation (instruments); comprehensive and equitable care, building bonds and trust (purposes and products). Nursing, in this process and within a biomedical logic in the service, faces overload, pressure and devaluation. Conclusions Nursing is configured as a strategic category in the performance of the Street Clinic and in the equity of care. There are facilities and difficulties to act independently with the multiprofissional team, especially with the biomedical model present in the service. It is necessary to build recognition of the performance of nursing and the empowerment of professionals in this category. Key messages Nursing still needs professional empowerment and recognition of the importance of their work process as essential in addressing vulnerabilities and equity in care. Bonding, trust and harm reduction are essential elements in the nursing work process in addressing the vulnerability of the Homeless Persons.