We detected no effects on game-farm mallards of dosing with 6 No.4 Bi shot or 6 No. 4 Fe shot, as compared with 0-dosed (control) ducks and with each other, on survival to 30 days post dosing, Hct values, body weight, or in the mean weights of kidneys, livers, gonads, and gizzards. All 240 Bi-dosed shot (6 shot in each of 40 ducks) were probably retained during the study. As many as 10 of the 240 Fe shot were probably dissolved, but they may have been voided. Dissolution rates for both Fe and Bi shot from DIy 0 to Day 30 were highly variable among ducks. The average dissolution rates were 70.2% for Bi shot and 61.1% for Fe shot. Females dissolved a higher percentage of the Fe shot than males, and males dissolved a higher percentage of Bi shot than Fe shot. Levels of Bi and Pb were determined in kidneys, livers, and gonads. There was 6.96 ppm, wet weight, Bi in kidneys, 2.23 ppm Bi in livers, and 0.468 ppm Bi in gonads of Bi-dosed ducks. Amounts of Pb in Bidosed ducks were 0.313 ppm in kidneys, 0.157 ppm in livers, and 0.096 ppm in gonads. Pb in the Bi shot averaged 0.00945%. Levels of Ca, P, Mg, Zn, Cu, Fe, and Sn were determined in kidneys, livers, gonads, blood plasma, and blood cells. There were several significant differences in the mean amounts of these elements among doses and between sexes; however, amounts of these elements in these organs and tissues in Bi-dosed ducks were not different from both 0-and Fe-dosed ducks. Many of the differences were sex related. Fe was higher in kidneys and livers of Fe-dosed ducks 3 than in 0-and Bi-dosed ducks and was much higher in the gonads of females than in males. Ca was higher in the livers of 0-dosed ducks than in Fe-and Bi-dosed ducks, was higher in the plasma of females than in males, and was up to 17 times higher in gonads of females than in males. Cu was higher in the livers and kidneys of males than in females. The MDL for Sn in the kidneys was 9.47 ppm;6 of 120 kidneys had Sn above the MDL. This study detected no toxic effects of dosing 6 No. 4 Bi shot in game-farm mallards.