Objective: to evaluate the efficacy of Bacterial Cellulose (BC) membrane dressings in the treatment of lower limb venous ulcers. Methods: we carried out a prospective, randomized, controlled study of 25 patients with chronic venous ulcer disease in the lower limbs from the Angiology and Vascular Surgery Service of the Federal University of Pernambuco Hospital and from the Salgado Polyclinic of the County Health Department, Caruaru, Pernambuco. We randomly assigned patients to two groups: control group, receiving dressings with triglyceride oil (11 patients) and experimental group, treated with BC membrane (14 patients). We followed the patients for a period of 120 days. Results: There was a reduction in the wound area in both groups. There were no infections or reactions to the product in any of the groups. Patients in the BC group showed decreased pain and earlier discontinuation of analgesic use. Conclusion: BC membrane can be used as a dressing for the treatment of varicose ulcers of the lower limbs.

Objetivou-se monitorar a evolução do processo cicatricial das lesões por pressão (LP) em pacientes hospitalizados emUnidades de Terapia Intensiva (UTI), a partir da aplicação da cobertura de celulose bacteriana (CB). Trata-se de uma sériede casos, amostra constituída por 10 pacientes internados na UTI. Foram excluídos crianças, adolescentes, e pacientes comoutros tipos de lesões de pele. Foram aplicadas as escalas preditivas de Braden e a de MEASURE. Realizado monitoramento fotográfico pelo programa MOWA®. A pesquisa foi desenvolvida no setor de terapia intensiva de um hospital universitário em Recife, Pernambuco. A maioria dos pacientes era do sexo feminino (60%), com média de idade de 60±12anos.Quanto as comorbidades, 3 pacientes apresentavam diabetes mellitus (DM), 2 hipertensão arterial sistêmica (HAS), 3 DMe HAS e 2 negaram doença crônica. Sete pacientes foram acompanhados por 30 dias, em média. O risco avaliado pelaescala de Braden foi de 9,66. As LP localizavam-se na região sacral, com área média de 84,48cm2 à avaliação inicial. Após30 dias de acompanhamento observou-se redução da área média das LP (-14,7cm²). A CB funcionou como barreira físicae indutor do remodelamento tecidual.Palavras -chave: Cicatrização; Lesão por pressão; Celulose; Cana-de-açúcar. ABSTRACTThe objective of this study was to monitor the evolution of the cicatricial process of pressure lesions (LP) in patientshospitalized in Intensive Care Units (ICU), from the application of bacterial cellulose (CB) coverage. This is a series of cases, a sample consisting of 10 patients hospitalized in the ICU. Children, adolescents, and patients with other types of skinlesions were excluded. Predictive scales of Braden and MEASURE were applied. Photographic monitoring carried out bythe MOWA® program. The research was developed in the intensive care sector of a university hospital in Recife, Pernambuco. The majority of the patients were female (60%), with a mean age of 60 ± 12 years. As for comorbidities, 3 patientshad diabetes mellitus (DM), 2 systemic arterial hypertension (SAH), 3 DM and SAH and 2 denied chronic disease. Sevenpatients were followed for 30 days, on average. The risk assessed by the Braden scale was 9.66. LPs were located in thesacral region, with a mean area of 84.48 cm2 at the initial evaluation. After 30 days of follow-up, we observed a reductionin the mean area of LP (-14.7 cm²). CB worked as a physical barrier and inducer of tissue remodeling.Keywords: Wound healing; Pressure injury; Cellulose; Sugar cane.

A hydrogel of bacterial cellulose of 0.8%, biopolymer produced from sugarcane molasses and synthesized from a bacteria called Zoogloea sp., was analyzed for its composition and tested by two routes of administration, subcutaneous and intraperitoneal, to clarify the local and systemic adverse effects after skin implantation in Wistar rats (24 males, 24 females, 55 days old). Analysis of two samples of BC films indicates carbon (42.94%; 43.43%), hydrogen (6.73%; 6.76%), nitrogen (0.28%, 0.23%) and oxygen (50.05%, 49.58%). No abnormal behavior, clinical signs of chronic toxicity or inflammation were observed. There was no change in liver injury biomarker levels (ALT, AST and ALP), as well as in renal histology, where it was evaluated to signs of tubular cell injury, glomerular or vascular damage, and renal morphometry, in which it was quantified the number of renal corpuscles, the number of cells per glomerulus and the capsular space area. Thus, the absence of signs and symptoms of toxicity suggests that subcutaneous or intraperitoneal injections of these polymers may be used in clinical situations.

The purpose of the present study was to report a case of an elongated styloid process in a dry human skull and present its biometrical values. The styloid processes of the skull from an 80-year-old Brazilian female individual were inspected and 10 measures were performed bilaterally. Despite small differences between the right and left styloid processes regarding the antero-posterior and lateral-medial widths on the three thirds measured, one must highlight the considerable differences showed on the total length of the styloid process (left side: 65.94; right side: 28.90) and on the length of the sheath of the styloid process, which was of 30.01mm on the left side and it was not acquired on the right side because of its small dimensions.  The paper discusses its findings from an anatomical and clinical perspectives, providing anatomical basis for a better understanding of the Eagle’s syndrome.

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