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Two synthetic peptides containing amino acid sequences analogous to the envelope glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy associated virus (LAV) were produced and used to immunize rabbits. The subsequent rabbit antisera neutralized HTLV‐III infectivity in vitro. The two synthetic peptides corresponded to regions associated with the gp120 or gp41 subunits respectively, of human immunodeficiency virus (HIV). This data indicates that at least two neutralizing epitopes are present on the envelope glycoprotein of HIV and these epitopes are associated with two distinct virus envelope glycoproteins. Antisera generated against these peptides neutralized infectivity of two different isolates of HTLV‐III. The data is discussed in terms of possible strategy for developing an effective vaccine against the etiologic agents of acquired immune deficiency syndrome (AIDS).

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When a waterborne outbreak of gastroenteritis and hepatitis occurred in Georgetown, Texas, in June 1980, human enteric viruses were isolated from two of the city's wells and from a 720‐L sample of the city's potable water. Hepatitis A virus was also detected in the sewage and in one well‐water sample. The demonstration of viruses in the groundwater supply during a disease outbreak has implications for other communities that rely on groundwater and practice little or no water treatment.