Internal root resorption is the progressive destruction of intraradicular dentin along the canal wall as a result of clastic activity. Perforating internal root resorption poses a diagnostic and treatment challenge to the clinician. Poor prognosis of such teeth makes extraction a treatment option. Presented herein is a case report of a mandibular second premolar with advanced perforating internal root resorption in the middle third of the root. Advanced diagnostic method, cone-beam computed tomography (CBCT) was used for definitive diagnosis and treatment planning. Sectional obturation with gutta-percha was performed up to the resorptive defect and mineral trioxide aggregate (MTA) was used to fill the resorptive defect and rest of the canal space. At a follow-up of 3 years, the patient was clinically asymptomatic with good bone repair around the resorptive defect.
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