Coronal fractures of permanent dentition are the most frequent type of dental injury. Fractured anterior teeth are usually treated with conventional post and core and crown techniques, after being treated endodontically. If the original tooth fragment is retained following fracture, the natural tooth structures can be reattached using adhesive protocols. Fiber-reinforced post makes the reattachment of the crown esthetically possible with minimal preparation and reduces the possibility of tooth fracture during function. This paper presents the therapeutic approach of reattachment of crown fragment to the tooth at the cervical and middle third levels.
A series of novel 5‐((3aR,5S,6S,6aR)‐6‐((1‐(4‐chlorophenyl)‐1H‐1,2,3‐triazol‐4‐yl)methoxy)‐2,2‐dimethyltetrahydrofuro[2,3‐d][1,3]dioxol‐5‐yl)‐3‐(4‐fluorophenyl)‐6‐phenyl‐3,3a,5,6‐tetrahydroisoxazolo[3,4‐d]thiazoles 10a–g were synthesized by the reaction of chalcone derivatives of 2‐((3aR,5S,6S,6aR)‐6‐((1‐(4‐chlorophenyl)‐1H‐1,2,3‐triazol‐4‐yl)methoxy)‐2,2‐dimethyltetrahydrofuro[2,3‐d][1,3]dioxol‐5‐yl)‐3‐phenylthiazolidin‐4‐one 9 with hydroxylamine hydrochloride. The chemical structures of newly synthesized compounds were elucidated by IR, NMR, MS, and elemental analysis. The compounds 10 a–g were evaluated for their nematicidal activity against Dietylenchus myceliophagus and Caenorhabditis elegans; compound 10e and 10f showed appreciable nematicidal activity. Further, the compounds 10a – g were screened for their antifungal activity against Candida albicans (ATCC 10231), Aspergillus fumigates (HIC 6094), Trichophyton rubrum (IFO 9185), and Trichopyton mentagrophytes (IFO 40996). The compounds 10b and 10f displayed notable antifungal activity against all the microorganisms employed. The activity of these compounds is almost equal to the standard. It is also interesting to note that the compounds 10b and 10f and 10g showed activity towards C. albicans at the concentration of 3.75 μM, which is less than the concentration of the standard Amphotericin B.
Aims: The aim of this study is to evaluate and compare the surface deformation and cyclic fatigue resistance of Hyflex controlled memory (CM) and Hyflex electric discharge machining (EDM) files following instrumentation and heat sterilization. Subjects and Methods: Thirty Hyflex CM and thirty Hyflex EDM files were selected and profilometric images taken. Sixty extracted molars were decoronated, cleaning and shaping done with files, and subjected to autoclaving. Profilometric images were taken after instrumentation and sterilization. Cyclic fatigue testing was done at 30° and 60° in a custom-made jig. Statistical Analysis Used: The Mann–Whitney test was used to compare profilometer and cyclic fatigue values between Hyflex CM and Hyflex EDM groups, whereas Friedman's and Wilcoxon signed-rank test were used for intragroup comparisons. Results: Intact Hyflex EDM files showed higher surface roughness values compared to Hyflex CM. Hyflex CM showed an increase in surface roughness after instrumentation and sterilization that was statistically significant while Hyflex EDM showed no statistical significance both after instrumentation and sterilization. Hyflex EDM showed a significantly higher mean number of cycles to failure than Hyflex CM at both degrees. Conclusions: Hyflex EDM files are able to maintain their surface topography and also have cyclic fatigue resistance better than Hyflex CM after both instrumentation and sterilization.
Deep Drawing (DD) process is the one in which a punch forces a flat sheet metal blank into a die cavity. DD can also be described as the process which involves conversion of flat thin sheet metal blanks into parts of desired shape. Little work is available in the applications of DD processes at elevated temperatures which is going to be a very important manufacturing application in the coming decades. Deep Drawing (DD) is one of the sheet metal forming processes widely used in automobile, aerospace, electronics and allied industries to produce the hollow parts. The improvement in the deep drawing manufacturing process with latest methodologies leads to developments in the automobile and other sheet metal industries. Still today, this process of analysis and design is an art than science. Presently, the conventional deep drawing (CDD) operation is carried out at room temperature in industries. Although the deep drawing process of high strength / low formability metals has an extensive industrial application area, deep drawing at room temperature has serious difficulties because of the large amount of deformations revealed and high flow stresses of the materials. The present paper gives an overview of deep drawing process, its classification along with advantages, limitations and applications.
The aim of study was to synthesize a new series of thiazolidinedione's. Thiazolidinedione's or glitziness forms a significant class of drugs which exhibit biological activities ranging from antidiabetic, anti-inflammatory, antibacterial, antifungal, antiviral and anticancer. In the present study reported a systematic synthesis of thiazolidinedione analogues. A new series of 2, 4-thiazolidinedione based derivatives have been synthesized by the condensation of various substituted phenoxy benzene amines and 4'-chlorosulphonyl 5-benzylidene-2, 4-thiazolidinedione. The structure of these compounds were established by IR and 1 H NMR. These new compounds (F1-F7) were evaluated for their antidiabetic activity on albino rats. Most of the compounds showed significant antidiabetic activity when compared with the standard drug metformin.
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